Takuro Igawa
Okayama University
CyclinInternal medicinePathologyLymphatic systemCyclin D1ImmunologyImmunohistochemistryBiopsyCastleman diseasePlasma cellMantle cell lymphomaLungLymphomaLymphMucosa-associated lymphoid tissueIgG4-related diseaseCyclin D2Differential diagnosisLymph nodeAbdominal painLesionPlasmablastic lymphomaCell cycleGene rearrangementCancer researchHistologyMedicineBiologyGastroenterology
22Publications
5H-index
88Citations
Publications 22
Newest
#1Sawako OnoH-Index: 1
#2Yasuharu SatoH-Index: 32
Last. Tadashi YoshinoH-Index: 77
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#2Takuro Igawa (Okayama University)H-Index: 5
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Abstract The diagnosis of leptomeningeal metastases is sometimes difficult when the cytology of cerebrospinal fluid is negative. We report a rare case of leptomeningeal metastases that required differentiation from paraneoplastic limbic encephalitis. A 67-year-old man with extensive-stage small cell lung cancer was admitted for a sudden decrease in the level of consciousness. He suffered memory disturbances that began the day before admission. Diffusion-weighted and fluid-attenuated inversion re...
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Plasma cell type idiopathic multicentric Castleman disease (PC-iMCD) occasionally manifests as parenchymal lung disease. This study aimed to elucidate the detailed clinicopathological features of lung lesions in PC-iMCD and compare the findings with those in immunoglobulin (Ig) G4-related disease (IgG4-RD), the most difficult differential diagnosis of PC-iMCD. We analyzed the clinicopathological findings and immunohistochemical expression patterns of interleukin-6 (IL-6) and Igs in lung specimen...
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#1Hiroki Kobayashi (Okayama University)H-Index: 1
#1Hiroki Kobayashi (Okayama University)H-Index: 13
Last. Yoshinobu Maeda (Okayama University)H-Index: 29
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Breast involvement of Adult T-cell leukemia-lymphoma (ATLL) is extremely rare, and the data on the characteristics are limited. We herein describe a 49-year-old woman who presented with skin involvement of ATLL. Positron emission tomography/computed tomography showed bilateral breast lesions. Although the patient once achieved a complete metabolic response, a relapse of her ATLL occurred. The patient received subsequent allogeneic hematopoietic stem cell transplantation (HSCT). To our knowledge,...
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#1Hirotsugu Yamamoto (Okayama University)H-Index: 5
#2Toshiyuki Aokage (Okayama University)H-Index: 10
Last. Hiromichi Naito (Okayama University)H-Index: 10
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Prolonged intestinal cold storage causes considerable mucosal breakdown, which could bolster bacterial translocation and cause life-threatening infection for the transplant recipient. The intestine has an intraluminal compartment, which could be a target for intervention, but has not yet been fully investigated. Hydrogen gas exerts organ protection and has used been recently in several clinical and basic research studies on topics including intestinal transplantation. In this study, we aimed to ...
1 CitationsSource
#1Akihiro Kawatsuki (Okayama University)
#2Takuro Igawa (Okayama University)H-Index: 5
Last. Tadashi Yoshino (Okayama University)H-Index: 77
view all 6 authors...
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#1Kohei Taniguchi (Okayama University)H-Index: 4
#2Shinichi Takada (Memorial Hospital of South Bend)
Last. Tadashi Yoshino (Okayama University)H-Index: 77
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Pleomorphic lobular carcinoma (PLC) is a histological variant of invasive lobular carcinoma (ILC) and is associated with worse prognosis than classical ILC. It exhibits a greater degree of cellular atypia and pleomorphism and is occasionally accompanied with apocrine morphology. We investigated the immunohistochemical characteristics of samples from 31 Japanese patients with PLC to elucidate the clinicopathological characteristics of PLC including androgen receptor (AR) immunoreactivity. The sur...
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#1Akio Sakatani (Okayama University)
#2Takuro Igawa (Okayama University)H-Index: 5
Last. Tadashi Yoshino (Okayama University)H-Index: 77
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Classic Hodgkin lymphoma (CHL) is a lymphoid neoplasia characterized by the presence of large tumor cells, referred to as Hodgkin and Reed-Sternberg (HRS) cells, originating from B-cells in an inflammatory background. As the clinical significance of B-cell markers has yet to be fully elucidated, this study aimed to clarify the clinicopathological significance of CD79a in 55 patients with CHL. They were immunohistochemically divided into two groups, comprising of 20 CD79a-positive and 35 CD79a-ne...
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#1Yanyan Han (Okayama University)H-Index: 1
#2Takuro Igawa (Okayama University)H-Index: 5
Last. Yasuharu Sato (RMIT: RMIT University)H-Index: 32
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Plasma cell-type Castleman disease (PCD) is a rare idiopathic atypical lymphoproliferative disorder. It is difficult to differentiate between PCD and IgG4-related disease (IgG4-RD) based on histology alone. As PCD often presents with abundant hemosiderin deposition, lymph node lesions obtained from 22 PCD patients and 12 IgG4-RD patients were analyzed using Prussian blue staining to clarify whether hemosiderin deposition is effective in distinguishing between these two diseases. The analysis dis...
2 CitationsSource
#1Chihiro Kageyama (RMIT: RMIT University)H-Index: 1
#2Takuro Igawa (Okayama University)H-Index: 5
Last. Yasuharu Sato (RMIT: RMIT University)H-Index: 32
view all 14 authors...
: Castleman-Kojima disease, also known as idiopathic multicentric Castleman disease with TAFRO syndrome (iMCD-TAFRO), is a recently recognized systemic inflammatory disorder with a characteristic series of clinical symptoms, including thrombocytopenia (T), anasarca (A), fever (F), reticulin fibrosis (R), and organomegaly (O). Patients with iMCD-TAFRO often develop severe abdominal pain, elevated alkaline phosphatase levels, and systemic inflammation, but the etiological factors are unknown. To i...
1 CitationsSource