Luca Frulloni
University of Verona
Internal medicineRadiologySurgeryPathologyRetrospective cohort studyIntensive care medicineImmunologyPancreatitisAcute pancreatitisPancreatic diseaseAutoimmune pancreatitisJaundicePancreasDiseasePancreatic ductPancreatic cancerIn patientIncidence (epidemiology)Diabetes mellitusMedicineGastroenterology
Publications 234
Chronic pancreatitis has been considered over the past years as a single disease, alcohol-induced and different from acute pancreatitis, in terms of etiology and prognosis. Actually, the introduction of a new concept of chronic pancreatitis, now considered as a fibroinflammatory process caused by multiple factors (toxic-metabolic, genetic, immunologic, obstructive), allow to better understand the pathogenesis of this complex disease. Furthermore, the discover of peculiar forms of chronic pancrea...
1 CitationsSource
#1Y. Issa (UvA: University of Amsterdam)H-Index: 11
Last. Joseph J. PalermoH-Index: 1
view all 196 authors...
Abstract Background The aim of the study was to evaluate the current opinion and clinical decision-making process of international pancreatologists, and to systematically identify key study questions regarding the diagnosis and treatment of chronic pancreatitis (CP) for future research. Methods An online survey, including questions regarding the diagnosis and treatment of CP and several controversial clinical case vignettes, was send by e-mail to members of various international pancreatic assoc...
13 CitationsSource
#1Laura Bernardoni (University of Verona)H-Index: 10
#2Stefano Francesco Crinò (University of Verona)H-Index: 13
Last. Armando Gabbrielli (University of Verona)H-Index: 26
view all 8 authors...
Background and study aims Pancreatic intraductal papillary mucinous neoplasms (IPMN) are cystic tumors of the pancreas characterized by a malignant potential. IPMN have been associated with recurrent pancreatitis (RP). Obstruction of the main pancreatic duct by thick mucus has been postulated to be the cause of pancreatitis. In a few isolated reports, pancreatic sphincterotomy (PS) has been reported to reduce the frequency of pancreatitis. The aim of this study was to assess the efficacy of PS i...
6 CitationsSource
#1Tsukasa IkeuraH-Index: 19
#2Kota KatoH-Index: 4
Last. Kazuichi OkazakiH-Index: 83
view all 8 authors...
#1Antonio Di Sabatino (UNIPV: University of Pavia)H-Index: 48
#2Federico Biagi (UNIPV: University of Pavia)H-Index: 38
Last. Gino Roberto Corazza (UNIPV: University of Pavia)H-Index: 87
view all 7 authors...
Abstract The progressively growing knowledge of the pathophysiology of a number of immune-mediated gastrointestinal and liver disorders, including autoimmune atrophic gastritis, coeliac disease, autoimmune enteropathy, inflammatory bowel disease, autoimmune hepatitis, primary sclerosing cholangitis, primary biliary cholangitis and autoimmune pancreatitis, together with the improvement of their detection methods have increased the diagnostic power of serum antibodies. In some cases – coeliac dise...
16 CitationsSource
#1Peter MacingaH-Index: 4
#2Lukáš BajerH-Index: 7
Last. Matthias Lӧhr (KI: Karolinska Institutet)
view all 16 authors...
Abstract Background Chronic pancreatitis is a known risk factor of pancreatic cancer (PDAC). A similar association has been suggested but not demonstrated for autoimmune pancreatitis (AIP). Objective The aim of our study was to identify and analyse all published cases of AIP and PDAC co-occurrence, focusing on the interval between the diagnoses and the cancer site within the pancreas. Methods Relevant studies were identified through automatic searches of the MEDLINE, EMBASE, Scopus, and Web of S...
#1Luca FrulloniH-Index: 58
#2Nicolò de PretisH-Index: 8
Last. Antonio AmodioH-Index: 13
view all 3 authors...
Autoimmune pancreatitis (AIP) is a fibro-inflammatory disease of the pancreas with a postulated immune-mediated mechanism (1,2). Two different histologic subtypes have been described, type 1 and type 2 AIP (3). Type 1 AIP is a more aggressive disease in terms of recurrences and extra-pancreatic organ involvement. International consensus diagnostic criteria (ICDC) have been established to classify the disease without definitive histology (4). ICDC introduced not otherwise specified (NOS) AIP as a...
5 CitationsSource
#1Nicolò de Pretis (University of Verona)H-Index: 8
#2Fabiana CapuanoH-Index: 2
Last. Luca FrulloniH-Index: 58
view all 14 authors...
OBJECTIVES: This study aimed to evaluate the clinical and radiological features and clinical outcomes of paraduodenal pancreatitis (PP). METHODS: A final diagnosis of PP was based on surgical specimens in resected patients and on imaging in nonoperated patients. Clinical, radiological, and pathological data were collected and reevaluated. RESULTS: We studied 120 patients, 97.5% of whom were drinkers and 97.5% were smokers. Symptoms at clinical onset were acute pancreatitis in 78 patients (65%) a...
11 CitationsSource
#1Stefano Francesco Crinò (University of Verona)H-Index: 13
#2Laura Bernardoni (University of Verona)H-Index: 10
Last. Armando Gabbrielli (University of Verona)H-Index: 26
view all 9 authors...
Background & Aims Santorinicele, a rare focal cystic dilation of the distal portion of the dorsal pancreatic duct at the minor papilla, can be a cause of recurrent acute pancreatitis (RAP). Endoscopic minor papilla sphincterotomy (EMPS) has been evaluated as a treatment in case reports but never systematically investigated. Methods We performed a retrospective analysis of the efficacy of EMPS in reducing episodes of pancreatitis. We collected data on 30 patients with santorinicele and RAP who un...
6 CitationsSource