Luca Frulloni
University of Verona
Internal medicineRadiologySurgeryPathologyRetrospective cohort studyIntensive care medicineImmunologyPancreatitisAcute pancreatitisPancreatic diseaseAutoimmune pancreatitisJaundicePancreasDiseasePancreatic ductPancreatic cancerIncidence (epidemiology)Diabetes mellitusMedicineGastroenterology
233Publications
44H-index
7,975Citations
Publications 241
Newest
Background and Study Aims On contrast-enhanced imaging studies, nonhypovascular (i. e., isovascular and hypervascular) patterns can be observed in solid pancreatic lesions (SPLs) of different nature, prognosis, and management. We aimed to identify endoscopic ultrasound (EUS) features of nonhypovascular SPLs associated with malignancy/aggressiveness. The secondary aims were EUS tissue acquisition (EUS-TA) outcome and safety in this setting of patients. Patients and Methods This prospective observ...
5 CitationsSource
#2Serena AmmendolaH-Index: 2
Last. Erminia ManfrinH-Index: 22
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Abstract Background/objectives Studies comparing EUS-guided fine-needle aspiration (EUS-FNA) with EUS-guided fine-needle biopsy (EUS-FNB) for the evaluation of pancreatic neuroendocrine tumors (pNETs) are lacking. We aimed at comparing EUS-FNA with EUS-FNB in terms of Ki-67 proliferative index (PI) estimation capability, cellularity of the samples, and reliability of Ki-67 PI/tumor grading compared with surgical specimens. Methods Patients diagnosed with pNETs on EUS and/or surgical specimens we...
1 CitationsSource
Abstract Background We aimed to assess factors impacting the endoscopic minor papilla sphincterotomy (EMPS) success rate, clinical efficacy, and safety in a large cohort of patients with symptomatic pancreas divisum (PD). Methods Retrospective study including patients with PD referred to the Pancreas Institute of Verona from May 2009 to May 2020 to undergo EMPS. The whole population was analyzed to assess EMPS technical success, defined as the rate of deep cannulation of the dorsal duct. Patient...
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#1Giulia De MarchiH-Index: 6
#2Antonio AmodioH-Index: 13
Last. Luca FrulloniH-Index: 44
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#1Gabriele Capurso (UniSR: Vita-Salute San Raffaele University)H-Index: 40
#2Salvatore Paiella (University of Verona)H-Index: 20
Last. Massimo FalconiH-Index: 85
view all 8 authors...
Abstract Pancreatic cancer is one of the main causes of cancer-related death worldwide, with a survival rate around 9%. In Italy 13,500 new cases of pancreatic cancer occurred in 2019. It is estimated that at least 5% have a hereditary background. Surveillance is advisable for healthy individuals with specific genetic syndromes with or without family history of pancreatic cancer or members of families with multiple cases of pancreatic cancer, irrespective of genetic syndromes. In 2010 the Italia...
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#1Antonio AmodioH-Index: 13
#2Giulia De MarchiH-Index: 6
Last. Luca FrulloniH-Index: 44
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Abstract Background Painless chronic pancreatitis (CP) is a rare form of the disease. Aim To evaluate the prevalence and the characteristics of this overlooked form of pancreatitis. Methods Patients with a diagnosis of CP and absence of pain were selected, excluding patients suffering from autoimmune pancreatitis. Clinical data, imaging features, and exocrine and endocrine function were therefore analyzed. Results Among 781 patients observed between 2010 and 2016, 74 patients with painless CP (9...
3 CitationsSource
Abstract Background and aims The aim of this study was to compare the performance of EUS-guided fine-needle biopsy using fork-tip (SharkCore, Medtronic, USA) or side-fenestrated (ProCore, Cook Medical, Limerick, Ireland) needles in patients with solid pancreatic lesions. Methods This is a randomized controlled study conducted in a single academic center, including patients who underwent sampling with the fork-tip or the side-fenestrated 22-gauge or 25-gauge needles. Three passes were performed, ...
10 CitationsSource
PURPOSE OF REVIEW Type 2 autoimmune pancreatitis (AIP) is a rare inflammatory disease of the pancreas. Very few data have been published on this particular subtype, which differs from the 'classical' IgG4-related type 1 AIP in terms of pathological features, epidemiology and risk of relapse. The aim of the current review is to summarize the available literature, suggesting a diagnostic and therapeutic approach to this disease. RECENT FINDINGS Based on the International Consensus Diagnostic Crite...
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#1Raffaele PezzilliH-Index: 41
#2Gabriele CapursoH-Index: 40
Last. Alessandro ZerbiH-Index: 48
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OBJECTIVE To evaluate a rapid checklist capable of identifying exocrine pancreatic insufficiency in outpatients. METHODS Prospective observational study of a multicenter cohort. RESULTS One hundred and two patients were enrolled; 61.8% of the patients had medically-treated benign or malignant pancreatic disease, and 38.2% had a pancreatic resection. Visual examination of the feces was evaluated in 84 patients and it was related to steatorrhea in 51 patients (50.0%). Receiver operating characteri...
1 CitationsSource
#1J-Matthias Löhr (Karolinska University Hospital)H-Index: 10
#2Ulrich Beuers (UvA: University of Amsterdam)H-Index: 66
Last. Heiko Witt (TUM: Technische Universität München)H-Index: 40
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The overall objective of these guidelines is to provide evidence-based recommendations for the diagnosis and management of immunoglobulin G4 (IgG4)-related digestive disease in adults and children. IgG4-related digestive disease can be diagnosed only with a comprehensive work-up that includes histology, organ morphology at imaging, serology, search for other organ involvement, and response to glucocorticoid treatment. Indications for treatment are symptomatic patients with obstructive jaundice, ...
13 CitationsSource