Anna Laura Capriotti
Sapienza University of Rome
Analytical chemistryDetection limitBiophysicsNanoparticleCationic liposomeMass spectrometryHigh-performance liquid chromatographyLiposomeChemistryIn vivoSample preparationPeptideProtein CoronaTandem mass spectrometryChromatographyProteomicsExtraction (chemistry)BiochemistryLiquid chromatography–mass spectrometryShotgun proteomicsComputational biologySolid phase extractionBiology
163Publications
38H-index
4,189Citations
Publications 166
Newest
#1Pasquale Linciano (UNIPV: University of Pavia)H-Index: 15
#2Fabiana Russo (University of Modena and Reggio Emilia)H-Index: 3
Last. Anna Laura Capriotti (Sapienza University of Rome)H-Index: 38
view all 14 authors...
Abstract null null The recent discovery of the novel heptyl phytocannabinoids cannabidiphorol (CBDP) and Δ9-tetrahydrocannabiphorol (Δ9-THCP) raised a series of questions relating to the presence and abundance of these new unorthodox compounds in cannabis inflorescence or derived products. As fresh inflorescence contains mainly their acid precursors, which are not commercially available, an ad hoc stereoselective synthesis was performed in order to obtain cannabidiphorolic acid (CBDPA) and Δ9-te...
Source
#1Carmela Maria Montone (Sapienza University of Rome)H-Index: 12
#2Sara Elsa Aita (Sapienza University of Rome)H-Index: 2
Last. Anna Laura Capriotti (Sapienza University of Rome)H-Index: 38
view all 10 authors...
Abstract null null The paper describes the development of a targeted quantitative method for the analysis of policosanols in hemp inflorescence. Policosanols are long chain aliphatic alcohols, with carbon chains typically in the range 20–36, with interesting biological activities. These compounds are typically separated by gas chromatography and only a few methods employ liquid chromatography for policosanols. In both cases, methods always include the derivatization of policosanols. In this stud...
Source
#1Anna Laura Capriotti (Sapienza University of Rome)H-Index: 38
#2Giuseppe Cannazza (University of Modena and Reggio Emilia)H-Index: 24
Last. Susy Piovesana (Sapienza University of Rome)H-Index: 27
view all 11 authors...
This review is a collection of recent applications of mass spectrometry studies for the characterization of phytocannabinoids in cannabis and hemp plant material and related products. The focus is mostly on recent applications using mass spectrometry as detector, in hyphenation to typical separation techniques (i.e., liquid chromatography or gas chromatography), but also with less common couplings or by simple direct analysis. The papers are described starting from the most common approach for t...
Source
#1Andrea CerratoH-Index: 8
#2Cinzia Citti (University of Modena and Reggio Emilia)H-Index: 11
Last. Aldo LaganàH-Index: 61
view all 11 authors...
Abstract Cannabis sativa is traditionally classified according to five chemotypes based on the concentration of the main phytocannabinoids tetrahydrocannabinol (THC), cannabidiol (CBD), and cannabigerol (CBG). However, cannabis chemovars and varieties very often present similar concentrations of such phytocannabinoids but different chemical profiles, which is unavoidably translated into different pharmacological effects when used for therapeutic purposes. For this reason, a more refined approach...
5 CitationsSource
#1Carmela Maria Montone (Sapienza University of Rome)H-Index: 12
#2Sara Elsa Aita (Sapienza University of Rome)H-Index: 2
Last. Anna Laura Capriotti (Sapienza University of Rome)H-Index: 38
view all 8 authors...
Chlorella vulgaris is a popular microalga used for biofuel production; nevertheless, it possesses a strong cell wall that hinders the extraction of molecules, especially lipids within the cell wall. For tackling this issue, we developed an efficient and cost-effective method for optimal lipid extraction. Microlaga cell disruption by acid hydrolysis was investigated comparing different temperatures and reaction times; after hydrolysis, lipids were extracted with n-hexane. The best recoveries were...
Source
#1Francesco TolomeoH-Index: 2
#2Fabiana Russo (University of Modena and Reggio Emilia)H-Index: 3
Last. Cinzia Citti (University of Modena and Reggio Emilia)H-Index: 11
view all 10 authors...
Abstract null null A sensitive and straightforward HPLC-UV method was developed for the simultaneous quantification of the two main impurities in “pure” commercial cannabigerol (CBG) samples. The identification of such impurities, namely cannabigerovarin (CBGV) and cannabigerobutol (CBGB), the propyl and butyl homologs of CBG, respectively, was accomplished employing the high-resolution mass spectrometry (HRMS) technique, and subsequently confirmed by comparison with the same compounds obtained ...
Source
Hemp and cannabis industry is undergoing a renewed interest due to legalization of marijuana (a topic that all countries are discussing, especially in recent years) and the growing importance of therapeutic properties of cannabinoids. Together with an increment in the production of hemp and recreational cannabis, there has been an increasing demand for accurate potency testing of products (i.e. quantification of main cannabinoids present in the plant in terms of weight percentage) prior commerci...
1 CitationsSource
#1Martina MaggiH-Index: 8
#2Andrea CerratoH-Index: 8
Last. Romà TaulerH-Index: 74
view all 11 authors...
Source
#1Chiara CavaliereH-Index: 43
#2Angela Michela Immacolata Montone (UNISA: University of Salerno)
Last. Anna Laura CapriottiH-Index: 38
view all 10 authors...
Soybeans (Glycine max) are an excellent source of dietary proteins and peptides with potential biological activities, such as antihypertensive, anti-cholesterol, and antioxidant activity; moreover, they could prevent cancer. Also, soy contains all the essential amino acids for nutrition; therefore, it represents an alternative to animal proteins. The goal of this paper was the comprehensive characterization of medium-sized and short peptides (two to four amino acids) obtained from simulated gast...
1 CitationsSource
#1Sara Elsa AitaH-Index: 2
Last. Aldo LaganàH-Index: 61
view all 8 authors...
Wild neotropical blueberries, endemic of Central and South American areas, are promising yet still undisclosed sources of bioactive compounds. Most research studies have addressed wild and cultivated blueberries from Europe and North America, despite the extremely wide variety of wild neotropical species. In the present paper, for the first time, the phenolic composition of Disterigma alaternoides was investigated through ultra-high-performance liquid chromatography coupled to high-resolution ma...
1 CitationsSource