Sharmela Sahathevan
National University of Malaysia
Vitamin D and neurologyInternal medicineFood groupEndocrinologyCross-sectional studyUltrasoundSerum albuminRandomized controlled trialIntensive care medicinePolyunsaturated fatty acidMalayHemodialysisKidney diseasePeritoneal dialysisDiseaseProtein–energy malnutritionWastingDialysisBody mass indexCreatininePopulationNutritional SupplementationContinuous ambulatory peritoneal dialysisPoor AppetiteWasting SyndromeQuadriceps muscleMaintenance hemodialysisProtein energy wastingEnd stage renal diseaseNutritional statusPhysiologyFatty acidMalnutritionAnthropometryMedicineEnvironmental health
25Publications
7H-index
157Citations
Publications 25
Newest
#1Sharmela Sahathevan (UKM: National University of Malaysia)H-Index: 7
#2Ban-Hock Khor (UKM: National University of Malaysia)H-Index: 6
Last. Tilakavati Karupaiah (Taylors University)H-Index: 14
view all 14 authors...
BACKGROUND: Muscle wasting, prevalent in hemodialysis (HD) patients diagnosed with protein energy wasting, represents an assessment challenge in the outpatient HD setting. Quadriceps muscle thickness (QMT) and cross-sectional area (CSA) assessment by ultrasound (US) is a potential surrogate measure for muscle wasting. We aimed to determine the validity of US to measure QMT and CSA against the gold standard, computed tomography (CT). METHODS: Twenty-six HD patients underwent US and CT scans on th...
1 CitationsSource
#1Ban-Hock Khor (UKM: National University of Malaysia)H-Index: 6
#2Sharmela Sahathevan (UKM: National University of Malaysia)H-Index: 7
view all 15 authors...
The metabolic impact of circulating fatty acids (FAs) in patients requiring hemodialysis (HD) is unknown. We investigated the associations between plasma triglyceride (TG) FAs and markers of inflammation, insulin resistance, nutritional status and body composition. Plasma TG-FAs were measured using gas chromatography in 341 patients on HD (age = 55.2 ± 14.0 years and 54.3% males). Cross-sectional associations of TG-FAs with 13 markers were examined using multivariate linear regression adjusted f...
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#1Sharmela Sahathevan (UKM: National University of Malaysia)H-Index: 7
#2Ban-Hock Khor (UKM: National University of Malaysia)H-Index: 6
Last. Tilakavati Karupaiah (Taylors University)H-Index: 14
view all 16 authors...
This study aimed to assess muscle wasting and risk of protein energy wasting (PEW) in hemodialysis (HD) patients using an ultrasound (US) imaging method. PEW was identified using the ISRNM criteria in 351 HD patients. Quadriceps muscle thickness of rectus femoris (RF) and vastus intermedius (VI) muscles and cross-sectional area (CSA) of the RF muscle (RFCSA) were measured using US and compared with other physical measures. Associations of US indices with PEW were determined by logistic regressio...
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#1Sharmela Sahathevan (UKM: National University of Malaysia)H-Index: 7
#2Ban-Hock Khor (UKM: National University of Malaysia)H-Index: 6
Last. Tilakavati Karupaiah (Taylors University)H-Index: 14
view all 7 authors...
Hemodialysis (HD) majorly represents the global treatment option for patients with chronic kidney disease stage 5, and, despite advances in dialysis technology, these patients face a high risk of morbidity and mortality from malnutrition. We aimed to provide a novel view that malnutrition susceptibility in the global HD community is either or both of iatrogenic and of non-iatrogenic origins. This categorization of malnutrition origin clearly describes the role of each factor in contributing to m...
1 CitationsSource
#1Ban-Hock Khor (UKM: National University of Malaysia)H-Index: 6
#2Ayesha Sualeheen (UKM: National University of Malaysia)H-Index: 2
view all 12 authors...
Sources of dietary phosphate differentially contribute to hyperphosphatemia in maintenance haemodialysis (MHD) patients. This cross-sectional study in Malaysia investigated association between dietary patterns and serum phosphorus in MHD patients. Dietary patterns were derived by principal component analysis, based on 27 food groups shortlisted from 3-day dietary recalls of 435 MHD patients. Associations of serum phosphorus were examined with identified dietary patterns. Three dietary patterns e...
Source
#1Fatin Athirah Pauzi (UPM: Universiti Putra Malaysia)H-Index: 1
#2Sharmela Sahathevan (UKM: National University of Malaysia)H-Index: 7
Last. Zulfitri Azuan Mat Daud (UPM: Universiti Putra Malaysia)H-Index: 7
view all 8 authors...
End-stage renal disease patients undergoing maintenance hemodialysis (HD) are vulnerable to the protein energy wasting (PEW) syndrome. Identification and diagnosis of PEW relies on clinical processes of judgment dependent on fulfilling multiple criteria drawn from serum biochemistry, weight status, predictive muscle mass, dietary energy and protein intakes. Therefore, we sought to explore the biomarkers’ signature with plasma metabolites of PEW by using 1H-nuclear magnetic resonance for an untar...
2 CitationsSource
#1Ayesha Sualeheen (UKM: National University of Malaysia)H-Index: 2
#2Ban-Hock Khor (UKM: National University of Malaysia)H-Index: 6
Last. Zaki Morad (National Kidney Foundation)H-Index: 10
view all 19 authors...
Objective This study aimed to (i) determine habitual dietary patterns of Malaysian patients on hemodialysis (HD) and (ii) examine their association with nutritional status. Methods An a posteriori approach examined 3-day dietary recalls of 382 multiethnic Malaysian patients on HD, leading to short-listing of 31 food groups. Dietary patterns were derived through principal component analysis. Sociodemographic and lifestyle characteristics together with nutritional parameters were examined for asso...
8 CitationsSource
#2Zu-Wei YeakH-Index: 1
Last. Zulfitri Azuan Mat DaudH-Index: 7
view all 12 authors...
A rapid and reliable tool appropriate to quantifying macronutrient and micronutrient intakes in diets consumed by Malaysian hemodialysis (HD) patients is lacking. We aimed to develop and validate a novel HD-food frequency questionnaire (HD-FFQ) to assess habitual nutritional intakes of HD patients with diverse ethnic backgrounds. This study was conducted in three phases. In Phase I, a HD-FFQ comprising 118 food items was developed using 3-day diet recalls (3DDR) from 388 HD patients. Phase II wa...
1 CitationsSource
#1Birinder Kaur Sadu Singh (UKM: National University of Malaysia)H-Index: 1
#2Sreelakshmi Sankara Narayanan (Taylors University)H-Index: 4
Last. Tilakavati Karupaiah (Taylors University)H-Index: 14
view all 8 authors...
: Lipid emulsions (LEs), an integral component in parenteral nutrition (PN) feeding, have shifted from the primary aim of delivering non-protein calories and essential fatty acids to defined therapeutic outcomes such as reducing inflammation, and improving metabolic and clinical outcomes. Use of LEs in PN for surgical and critically ill patients is particularly well established, and there is enough literature assigning therapeutic and adverse effects to specific LEs. This narrative review contra...
3 CitationsSource
#1Ban-Hock Khor (UKM: National University of Malaysia)H-Index: 6
#2Sharmela Sahathevan (UKM: National University of Malaysia)H-Index: 7
Last. for PaTCH InvestigatorsH-Index: 1
view all 15 authors...
Abstract Objectives The aims of this study were threefold: first, to assess the dietary fatty acid (FA) intake and blood FA status in Malaysian patients on hemodialysis (HD); second, to examine the association between dietary FA intakes and blood FA profiles in patients on HD; and third, to determine whether blood FAs could serve as a biomarker of dietary fat intake quality in these patients. Methods Using 3 d of dietary records, FA intakes of 333 recruited patients were calculated using a food ...
3 CitationsSource