Krishnaswamy Chandrasekaran
Mayo Clinic
Internal medicineRadiologySurgeryUltrasoundCardiologyHemodynamicsMitral valveHeart failureAtrial flutterVentricleAtrial fibrillationElectrocardiographyHeart diseaseInfective endocarditisTransplantationIn patientMyocardial infarctionDiastoleMedicineEjection fraction
Publications 163
#1Vinayak Kumar (Mayo Clinic)H-Index: 3
#2Armando Manduca (Mayo Clinic)H-Index: 59
Last. Nandan S. Anavekar (Mayo Clinic)H-Index: 25
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BACKGROUND Myocardial volume is assumed to be constant over the cardiac cycle in the echocardiographic models used by professional guidelines, despite evidence that suggests otherwise. The aim of this paper is to use literature-derived myocardial strain values from healthy patients to determine if myocardial volume changes during the cardiac cycle. METHODS A systematic review for studies with longitudinal, radial, and circumferential strain from echocardiography in healthy volunteers ultimately ...
#1Hilmi Alnsasra (Mayo Clinic)H-Index: 4
#2Rabea Asleh (Mayo Clinic)H-Index: 19
Last. Sudhir S. Kushwaha (Mayo Clinic)H-Index: 53
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Background Myocardial fibrosis is an important contributor for development of diastolic dysfunction. We investigated the impact of sirolimus as primary immunosuppression on diastolic dysfunction and fibrosis progression among heart transplantation recipients. Methods and Results In 100 heart transplantation recipients who were either treated with a calcineurin inhibitor (CNI) (n=51) or converted from CNI to sirolimus (n=49), diastolic function parameters were assessed using serial echocardiogram...
#1Vinayak Kumar (Mayo Clinic)H-Index: 3
#2Alexander J. Ryu (Mayo Clinic)H-Index: 5
Last. Nandan S. Anavekar (Mayo Clinic)H-Index: 25
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BACKGROUND The professional guidelines assume that the myocardial volume in systole (MVs) is equal to that in diastole (MVd), despite some limited evidence that points to the contrary. The aim of this manuscript is to determine whether this is true in healthy myocardium using gold standard cardiac MRI, as well as transthoracic echocardiography (TTE). The secondary aim is to determine whether there are similar MV changes in patients with heart failure with reduced ejection fraction (HFrEF). METHO...
2 CitationsSource
#1Alexander J. Ryu (Mayo Clinic)H-Index: 5
#2Vinayak Kumar (Mayo Clinic)H-Index: 3
Last. Nandan S. Anavekar (Mayo Clinic)H-Index: 25
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Abstract Background In patients with normal left ventricular ejection fraction, it may be difficult to distinguish between the normal and diseased heart. Novel assessments of ventricular function, such as extracellular volume imaging, myocardial perfusion imaging and myocardial contraction fraction are emerging to better assess disease burden in these cases. This study endeavored to determine whether the ratio of myocardial volume in systole to myocardial volume in diastole (MVs/MVd), differs be...
1 CitationsSource
#1Nadia AkhiyatH-Index: 1
#1Nadia S Akhiyat (Mayo Clinic)
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Introduction: Cardiovascular disease remains the leading cause of morbidity and mortality in patients with amyloid light chain (AL) amyloidosis. Current prognostic evaluation in AL cardiomyopathy (...
#1Aravind Sampath (Apollo Hospitals)
#1Aravind Sampath (Apollo Hospitals)
Last. Ramesh C. Bansal (LLUMC: Loma Linda University Medical Center)H-Index: 23
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Isolated single coronary artery (SCA) is a rare anomaly. Current classification of left and right is further classified based on the course of the anomalous vessel. We report two SCA L cases where right coronary artery (RCA) arose from mid-left anterior descending coronary artery (LAD). Our observation is a variation from the current Lipton classification SCA L Type II where RCA arose from left coronary artery before the LAD, in our cases the RCA arose from mid LAD after the first septal perfora...
Percutaneous mitral valve repair is an accepted treatment of choice in Europe and North America for severe primary or secondary mitral regurgitation, in highly symptomatic patients for whom surgical repair is prohibitively high risk. We describe the first use of the MitraClip in India in a frail elderly female with symptomatic heart failure from severe primary mitral regurgitation who was considered high risk for surgical repair. She had substantial improvement in her symptoms as well as quality...
#1Georgios Christopoulos (Mayo Clinic)H-Index: 3
#2Zachary Barrett-O'Keefe (Mayo Clinic)
Last. Krishnaswamy Chandrasekaran (Mayo Clinic)H-Index: 35
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The clinical distinction between athlete's heart and structural heart disease in the echocardiography laboratory is often challenging. We present a case where athletic heart syndrome was promptly differentiated from pathology with a simple maneuver during echocardiography.
#1Ratnasari Padang (Mayo Clinic)H-Index: 13
#2Nikhitha Chandrashekar (Mayo Clinic)H-Index: 1
Last. Garvan C. Kane (Mayo Clinic)H-Index: 50
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AIMS: Right ventricular dysfunction (RVD) is an important determinant of functional status and survival in various diseases states. Data are sparse on the epidemiology and outcome of patients with severe RVD. This study examined the characteristics, aetiology, and survival of patients with severe RVD. METHODS AND RESULTS: Retrospective study of consecutive patients with severe RVD diagnosed by transthoracic echocardiography (TTE) between 2011 and 2015 in a single tertiary referral institution. P...
17 CitationsSource