Antonio Di Sabatino
University of Pavia
Internal medicinePathologyImmunologyInfliximabInflammatory bowel diseaseCytokineDiseaseCrohn's diseaseAtrophic gastritisCoeliac diseaseUlcerative colitisSpleenSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Coronavirus disease 2019 (COVID-19)In patientCancer researchMedicineBiologyImmune systemGastroenterology
Publications 253
#1Majken LindholmH-Index: 2
#2Antonio Di Sabatino (UNIPV: University of Pavia)H-Index: 48
Last. Jens Kjeldsen (University of Southern Denmark)H-Index: 33
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BACKGROUND The laminin gamma 1 chain (LMγ1) is abundant along the crypt-villus axis in the intestinal basement membrane. AIMS We investigated whether a serological biomarker of laminin degradation was associated with disease activity in patients with Crohn's disease (CD) and in rats with dextran sulfate sodium (DSS)-induced colitis. METHODS Serum samples from CD patients (n = 43), healthy subjects (n = 19), and Sprague Dawley rats receiving 5-6% DSS water for five days and regular drinking water...
#1Carlo Maria Rossi (UNIPV: University of Pavia)
#2Marco Vincenzo Lenti (UNIPV: University of Pavia)H-Index: 16
Last. Antonio Di Sabatino (UNIPV: University of Pavia)H-Index: 48
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Abstract null null Allergic disorders target a young population, are increasing in both incidence and prevalence and are associated with significant disease burden. They result from the complex interplay between (epi)genetic and environmental factors, resulting in a Th2 inflammatory process targeting the epithelium of the respiratory tract (allergic rhinitis and asthma), skin (atopic dermatitis), and gastrointestinal tract (food allergy). Although the exact pathogenic mechanisms remain elusive, ...
#1Carlo Robotti (UNIPV: University of Pavia)H-Index: 2
#2Antonio Schindler (University of Milan)H-Index: 27
Last. Francesco Mozzanica (University of Milan)H-Index: 14
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Abstract null null Introduction null Vocal tract discomfort (VTD), dysphonia, and laryngopharyngeal reflux (LPR) symptoms are complaints frequently reported by amateur singers. There are two aims of this study. The first is to evaluate the prevalence of these symptoms using validated questionnaires. The second is to correlate singing-related variables with the questionnaire responses. null null null Methods null A total of 392 amateur choir singers (ACS) and 514 control subjects completed an onl...
#1Tiziano Perrone (UNIPV: University of Pavia)H-Index: 9
#2Gino SoldatiH-Index: 26
Last. Antonio Di Sabatino (UNIPV: University of Pavia)H-Index: 48
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Objectives Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection can generate severe pneumonia associated with high mortality. A bedside lung ultrasound (LUS) examination has been shown to have a potential role in this setting. The purpose of this study was to evaluate the potential prognostic value of a new LUS protocol (evaluation of 14 anatomic landmarks, with graded scores of 0-3) in patients with SARS-CoV-2 pneumonia and the association of LUS patterns with clinical or labo...
16 CitationsSource
#1Federica Melazzini (UNIPV: University of Pavia)H-Index: 16
#2Marta Colaneri (UNIPV: University of Pavia)H-Index: 10
Last. Antonio Di Sabatino (UNIPV: University of Pavia)H-Index: 48
view all 18 authors...
Preliminary evidence supports the notion that COVID-19 patients may have an increased susceptibility to develop venous thromboembolism (VTE). However, the magnitude of this association still needs to be defined. Furthermore, clinical predictors of thrombogenesis, and the relationship with the inflammatory status are currently unknown. On this basis, we conducted a retrospective, observational study on 259 consecutive COVID-19 patients admitted to an academic tertiary referral hospital in Norther...
1 CitationsSource
COVID-19, caused by SARS-CoV-2, has become a global threat in a matter of months. In particular, Italy has been one of the most affected areas worldwide. Data regarding the clinical picture and clinical course of COVID-19 are still lacking, especially in non-Asian populations. COVID-19 usually causes an influenza-like syndrome, including cough, fever, sore throat, muscle pain, and in some cases a more severe clinical picture, including interstitial pneumonia with acute respiratory distress syndr...
#1Marco Vincenzo Lenti (UNIPV: University of Pavia)H-Index: 16
#2S. Cococcia (UNIPV: University of Pavia)H-Index: 6
Last. Antonio Di Sabatino (UNIPV: University of Pavia)H-Index: 48
view all 7 authors...
#1Martina Costetti (UNIPV: University of Pavia)H-Index: 1
#2Annalisa Schiepatti (UNIPV: University of Pavia)H-Index: 8
Last. Gino Roberto Corazza (UNIPV: University of Pavia)H-Index: 86
view all 12 authors...
Abstract null null Background null Clinical elements differentiating enteropathy due to angiotensin II-receptor-blockers (ARBs-E) from coeliac disease (CD) are poorly defined. The histopathological features on duodenal and gastric biopsies in these patients still need to be investigated. null null null Aims null To describe the clinical phenotype of ARBs-E in comparison to CD, and the histological findings of gastric and duodenal biopsies in ARBs-E. null null null Methods null Clinical data of p...
1 CitationsSource
#1Pietro Lucotti (UNIPV: University of Pavia)H-Index: 2
#2Elisabetta Lovati (UNIPV: University of Pavia)H-Index: 6
Last. Antonio Di Sabatino (UNIPV: University of Pavia)H-Index: 48
view all 14 authors...
Abstract Background and aims Glucagon-like peptide GLP-1 and -2 have been shown to regulate immune responses in immune-mediated disorders, including Crohn’s disease (CD). Our aim was to investigate post-prandial GLP release and its potential link to chronic inflammation, insulin secretion/sensitivity and body composition changes in CD patients. Methods Fifteen patients with CD, 15 healthy controls (HC) and 15 patients with metabolic syndrome (MS) were recruited. All patients underwent assessment...
1 CitationsSource