Mario A. Gómez-Hurtado
Universidad Michoacana de San Nicolás de Hidalgo
Analytical chemistryAcetylationStereoisomerismCircular dichroismComputational chemistryDensity functional theoryOrganic chemistryChemistryVibrational circular dichroismMaterials scienceTwo-dimensional nuclear magnetic resonance spectroscopyAbsolute configurationAgeratinaCaesalpinia platylobaSpectroscopyMoleculeEnantiomerStereochemistrySingle crystalSupramolecular chemistry
32Publications
8H-index
133Citations
Publications 26
Newest
#1A. Del Moral-G (UMSNH: Universidad Michoacana de San Nicolás de Hidalgo)
#2Tzarara López-Luke (UMSNH: Universidad Michoacana de San Nicolás de Hidalgo)H-Index: 18
Last. Gerardo Rosas (UMSNH: Universidad Michoacana de San Nicolás de Hidalgo)H-Index: 12
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Abstract A time-dependent eco-friendly synthesis of Au assemblies was carried out using Taraxacum officinale plant extract in the present study. Au nanomaterials have potential applications in imaging therapy cancer diagnostics due to their biocompatibility and fluorescence response when irradiated with Ultraviolet light. Also, synthesis methods whose chemistry minimizes toxic residues are of interest to scientists, mainly when intended to use Au nanomaterials for biomedical treatments. Furtherm...
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#1Héctor M. Arreaga-González (IPN: Instituto Politécnico Nacional)H-Index: 3
#1Héctor M. Arreaga-González (IPN: Instituto Politécnico Nacional)
Last. Mario A. Gómez-Hurtado (UMSNH: Universidad Michoacana de San Nicolás de Hidalgo)H-Index: 8
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Since epoxythymols occur in Nature either as scalemic mixtures or as pure enantiomers, the knowledge of their chiral composition and of the absolute configuration (AC) of the dominant enantiomer turns out to be mandatory. This task has already been faced using 1,1-bis-2-naphthol (BINOL), as a chiral solvating agent in accurate 1H NMR quantifications to determine the enantiomeric ratio, and vibrational circular dichroism (VCD) to evidence the AC of the dominant enantiomer. We now explore the use ...
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#1Ana K. Villagómez-Guzmán (UMSNH: Universidad Michoacana de San Nicolás de Hidalgo)H-Index: 2
#2Gabriela Rodríguez-García (UMSNH: Universidad Michoacana de San Nicolás de Hidalgo)H-Index: 5
Last. Mario A. Gómez-Hurtado (UMSNH: Universidad Michoacana de San Nicolás de Hidalgo)H-Index: 8
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A known kaurenoic acid (1), together with a new kaurane derivative named 3α-isobutyryloxykaurenoic acid (2), was isolated from the roots of Lasianthaea aurea, a plant endemic to Mexico. The compounds were characterized using their physical and spectroscopic data. In order to verify the structure and absolute configuration of 2, the derived methyl ester 3, obtained after diazomethane treatment, was subjected to single-crystal X-ray diffraction analysis, whose Flack and Hooft parameter calculation...
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Abstract As it is difficult to study polyhydroxylated natural products by vibrational circular dichroism (VCD) due to their very limited solubility in infrared transparent solvents, 7-O-β-D-glucopyranosylchrysin (1), isolated from Mimosa rosei, was acetylated to provide 7-O-(2ʹʹ,3ʹʹ,4ʹʹ,6ʹʹ-tetraacetyl-β-D-glucopyranosyl)-5-acetylchrysin (2). Density functional theory (DFT) VCD spectra of 2 were calculated using the B3LYP, B3PW91, and PBEPBE functionals and the DGDZVP basis set to ascertain a go...
1 CitationsSource
Last. Rosa E. del RíoH-Index: 12
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#1Héctor M. Arreaga-González (UMSNH: Universidad Michoacana de San Nicolás de Hidalgo)H-Index: 3
#2Gabriela Rodríguez-García (UMSNH: Universidad Michoacana de San Nicolás de Hidalgo)H-Index: 5
Last. Mario A. Gómez-Hurtado (UMSNH: Universidad Michoacana de San Nicolás de Hidalgo)H-Index: 8
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The exceptional case of a natural compound that shows drastic absolute configuration variations within the same species was examined. Sequential samples of areolal (1) isolated from Piptothrix areolare showed dextrorotatory (ee 32%), almost racemic (ee 4%), levorotatory (ee 82%), and again dextrorotatory (ee 10%) values. Enantiomeric compositions of this epoxythymol derivative were determined from individual plant specimens collected from the same geographical location over a 46-day period, whic...
3 CitationsSource
#1Jairo J. Rojas-Ortiz (UMSNH: Universidad Michoacana de San Nicolás de Hidalgo)
#2Claudia Contreras-Celedón (UMSNH: Universidad Michoacana de San Nicolás de Hidalgo)H-Index: 6
Last. Carlos J. Cortes-García (UMSNH: Universidad Michoacana de San Nicolás de Hidalgo)H-Index: 4
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An eco-friendly methodology for the synthesis of novel Schiff base analogs of Raltegravir, an integrase inhibitor drug, is described. Thus, pertinence of these imine derivatives is related to Medicinal Chemistry to develop new anti-HIV compounds. Based on thorough search of the relevant literature, this is the first report of the synthesis of Schiff base using a Raltegravir drug fragment as amino component. In addition, these imines will be used as a synthetic precursor to prepare other biologic...
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#1Gabriela Rodríguez-García (UMSNH: Universidad Michoacana de San Nicolás de Hidalgo)H-Index: 5
#2Ana K. Villagómez-Guzmán (UMSNH: Universidad Michoacana de San Nicolás de Hidalgo)H-Index: 2
Last. Rosa E. del Río (UMSNH: Universidad Michoacana de San Nicolás de Hidalgo)H-Index: 12
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: Although podocephalol (1) and its derived acetate 2 were found in Lasianthaea podocephala four decades ago, and 1 was later detected in the essential oils of several vegetal species, its absolute configuration (AC) and conformational preferences remained to be established. The structures of ar-himachalene 1, now isolated from Lasianthaea aurea, and its derived acetate 2, were herein confirmed by extensive 1D and 2D nuclear magnetic resonance (NMR) studies, while the conformational preferences ...
5 CitationsSource