Alessandra Barassi
University of Milan
Troponin IVitamin D and neurologyEndocrinologySurgeryPathologyCardiologyChemistryImmunologyPancreatitisAcute pancreatitisPancreatic diseaseInflammationPancreasDiseaseErectile dysfunctionCreatinineEndothelial dysfunctionChromatographyMedicineGastroenterology
145Publications
21H-index
1,227Citations
Publications 102
Newest
#1Raffaele Pezzilli (University of Milan)H-Index: 41
#2Stefano CentanniH-Index: 28
Last. Alessandra BarassiH-Index: 21
view all 8 authors...
OBJECTIVES Gastrointestinal manifestations of coronavirus disease 19 (COVID-19) have been well established, but pancreatic involvement is under debate. Our aims were to evaluate the presence of acute pancreatitis in COVID-19 patients and to assess the frequency of pancreatic hyperenzymemia. METHODS From April 1, 2020, to April 30, 2020, 110 consecutive patients (69 males, 41 females; mean age, 63.0 years; range, 24-93 years) met these criteria and were enrolled in the study. The clinical data an...
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#1Giuseppe Ancona (University of Milan)H-Index: 4
#2Esther Merlini (University of Milan)H-Index: 11
Last. Giulia Marchetti (University of Milan)H-Index: 30
view all 11 authors...
Background We explored the long-term effects of cART on markers of gut damage, microbial translocation and paired gut/blood microbiota composition, with a focus on the role exerted by different drug classes. Methods We enrolled 41 cART naive HIV-infected subjects, undergoing blood and fecal sampling prior to cART (T0) and after 12 (T12) and 24 (T24) months of therapy. 15 HIV-uninfected individuals were enrolled as controls. We analyzed: (i) T-cell homeostasis (flow cytometry); (ii) microbial tra...
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#1Alessandra Barassi (University of Milan)H-Index: 21
#2Raffaele PezzilliH-Index: 41
Last. Stefano Centanni (University of Milan)H-Index: 28
view all 8 authors...
BACKGROUND: Vitamin D (VitD) deficiency has been reported to be associated with respiratory tract infection. In this work we evaluated the concentration of VitD in COVID-19 patients experiencing acute respiratory infections of different levels of severity excluding those who underwent invasive respiratory support. METHODS: The levels of serum VitD and C-reactive protein (CRP) were analyzed in 118 consecutive hospitalized COVID-19 patients (74M, 44F), confirmed with rRT-PCR. Of these patients wit...
1 CitationsSource
#1Giovanni Marfia (Aeronáutica)H-Index: 18
#1Giovanni Marfia (Aeronáutica)H-Index: 3
Last. Laura Riboni (University of Milan)H-Index: 29
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The severity of coronavirus disease 2019 (COVID-19) is a crucial problem in patient treatment and outcome. The aim of this study is to evaluate circulating level of sphingosine-1-phosphate (S1P) along with severity markers, in COVID-19 patients. One hundred eleven COVID-19 patients and forty-seven healthy subjects were included. The severity of COVID-19 was found significantly associated with anemia, lymphocytopenia, and significant increase of neutrophil-to-lymphocyte ratio, ferritin, fibrinoge...
4 CitationsSource
#1Giovanni Marfia (Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico)H-Index: 18
#2Stefania Elena Navone (Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico)H-Index: 18
Last. Laura Riboni (University of Milan)H-Index: 29
view all 15 authors...
1 CitationsSource
#1Giovanni Sotgiu (University of Sassari)H-Index: 52
#2Alessandra Barassi (University of Milan)H-Index: 21
Last. Stefano Centanni (University of Milan)H-Index: 4
view all 11 authors...
COVID-19 is an infectious disease caused by a novel coronavirus (SARS-CoV-2). The immunopathogenesis of the infection is currently unknown. Healthcare workers (HCWs) are at highest risk of infection and disease. Aim of the study was to assess the sero-prevalence of SARS-CoV-2 in an Italian cohort of HCWs exposed to COVID-19 patients. A point-of-care lateral flow immunoassay (BioMedomics IgM-IgG Combined Antibody Rapid Test) was adopted to assess the prevalence of IgG and IgM against SARS-CoV-2. ...
31 CitationsSource
#1Raffaele PezzilliH-Index: 41
#2Stefano CentanniH-Index: 28
Last. Alessandra BarassiH-Index: 21
view all 8 authors...
Background: Gastrointestinal manifestations of COVID-19 have been well established, but pancreatic involvement is under debate To evaluate the presence of acute pancreatitis in COVID-19 patient in a prospective, unicenter cohort study Methods: From April 1, 2020 to April 30, 2020, 110 consecutive patients (69 males, 41 females;mean age 63 0 years [range, 24-93 years]) met these criteria and were enrolled in the study The clinical data and serum activity of pancreatic amylase and lipase were assa...
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#1Luca MassaccesiH-Index: 10
#2Daniela GalimbertiH-Index: 61
Last. Emanuela GallieraH-Index: 23
view all 8 authors...
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#1Luca Massaccesi (University of Milan)H-Index: 10
#2Emanuela Galliera (University of Milan)H-Index: 23
Last. Massimiliano Marco Corsi Romanelli (University of Milan)H-Index: 13
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In the brain, Oxidative Stress (OS) contribute to structural and functional changes associated with vascular aging, such as endothelial dysfunction, extracellular matrix degradation, resulting in age-related reduced vasodilatation in response to agonists. For this reason, OS is considered a key factor in Alzheimer’s Disease (AD) development and recent evidence correlated oxidative stress with vascular lesion in the pathogenesis of AD, but the mechanism still need to be fully clarified.
7 CitationsSource
#1Matteo Basilissi (University of Milan)H-Index: 2
#2Camilla Tincati (University of Milan)H-Index: 17
Last. Giulia Marchetti (University of Milan)H-Index: 30
view all 9 authors...
: HIV infection causes the progressive depletion of CD4+ T-lymphocytes and profound modifications of T-cell homeostasis, which persist despite virologically-suppressive treatment and have been linked to a worse clinical outcome. Enduring alterations of the gastrointestinal tract may represent the underlying pathogenic mechanisms of these phenomena. Twenty-six HIV-infected subjects were assessed over a 12-month period following the introduction of antiretroviral therapy. 18 uninfected individuals...
2 CitationsSource