Martin J. J. Ronis
LSU Health Sciences Center New Orleans
EndocrinologyCYP2E1Gene expressionChemistryCaseinOxidative stressSteatosisSoy proteinOsteoblastGenisteinFatty liverIsoflavonesEthanolToxicityCytochrome P450BiochemistryBone resorptionMedicineBiologyMicrosome
219Publications
48H-index
6,736Citations
Publications 219
Newest
#1Hui-Yi Lin (LSU Health Sciences Center New Orleans)H-Index: 24
#2Qiufan Fu (LSU Health Sciences Center New Orleans)
Last. Michael E. Hagensee (LSU Health Sciences Center New Orleans)H-Index: 21
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Background Human papillomavirus (HPV) infection is a major cause of cervical cancer. Studies showed the onset of HPV carcinogenesis may be induced by oxidative stress affecting the host immune system. The association between antioxidants and oncogenic HPV remains unclear. In this study, we aim to identify antioxidants associated with vaginal HPV infection in women. Methods The associations between the 15 antioxidants and vaginal HPV infection status (no, low-risk, and high-risk HPV [LR- and HR-H...
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#1Haixia Lin (University of Arkansas for Medical Sciences)H-Index: 8
#2Mousumi ChaudhuryH-Index: 2
Last. Kelly E. Mercer (University of Arkansas for Medical Sciences)H-Index: 18
view all 8 authors...
Abstract Postnatal dietary modulation of microRNAs (miRNAs) and effects on miRNA-mRNA interactions in tissues remain unknown. This study aimed to investigate whether dietary factors (formula vs. breastfeeding) affect mammary miRNA expression, and determine if these changes are concurrent with developmental alterations of the mammary gland in neonatal piglets. Female Yorkshire/Duroc piglets were fed sow's milk or cow's milk- or soy-based infant formula (from postnatal day 2 to day 21; n=6/group)....
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#1Jin-Ran Chen (University of Arkansas for Medical Sciences)H-Index: 26
#2Oxana P. Lazarenko (University of Arkansas for Medical Sciences)H-Index: 18
Last. Martin J. J. Ronis (LSU Health Sciences Center New Orleans)H-Index: 48
view all 7 authors...
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#1Benjamin Jenkins (University of Cambridge)H-Index: 11
#2Martin J. J. Ronis (LSU: Louisiana State University)H-Index: 48
Last. Albert Koulman (University of Cambridge)H-Index: 33
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Typical lipidomics methods incorporate a liquid–liquid extraction with LC–MS quantitation; however, the classic sample extraction methods are not high-throughput and do not perform well at extracting the full range of lipids especially, the relatively polar species (e.g., acyl-carnitines and glycosphingolipids). In this manuscript, we present a novel sample extraction protocol, which produces a single phase supernatant suitable for high-throughput applications that offers greater performance in ...
2 CitationsSource
#1Martin J. J. Ronis (LSU Health Sciences Center New Orleans)H-Index: 48
#2Kelly E. MercerH-Index: 18
Last. David A. Welsh (LSU Health Sciences Center New Orleans)H-Index: 21
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Abstract We have previously demonstrated promotion of diethylnitrosamine (DEN) initiated liver tumorigenesis after feeding diets high in fat or ethanol (EtOH) to male mice. This was accompanied by hepatic induction of the proto-oncogene PIKE (Agap2). Switch of dietary protein from casein to soy protein isolate (SPI) significantly reduced tumor formation in these models. We have linked EtOH consumption in mice to microbial dysbiosis. Adoptive transfer studies demonstrate that microbiota from mice...
1 CitationsSource
#1Ashlee E Williams (LSU Health Sciences Center New Orleans)H-Index: 2
#2James Watt (LSU Health Sciences Center New Orleans)H-Index: 4
Last. Martin J. J. Ronis (LSU Health Sciences Center New Orleans)H-Index: 48
view all 14 authors...
Epidemiological evidence links polychlorinated biphenyls (PCBs) to skeletal toxicity, however mechanisms whereby PCBs affect bone are poorly studied. In this study, coplanar PCB 126 (5 mumol/kg) or corn oil vehicle was administered to N = 5-6 male and female, wild type (WT) or AhR-/- rats via intraperitoneal injection. Animals were sacrificed after four weeks. Bone length was measured; bone morphology was assessed by micro-computed tomography and dynamic histomorphometry. Reduced bone length was...
5 CitationsSource
#1Martin J. J. Ronis (LSU Health Sciences Center New Orleans)H-Index: 48
#2Huijing Xia (LSU Health Sciences Center New Orleans)H-Index: 19
Last. Kurt J. Varner (LSU Health Sciences Center New Orleans)H-Index: 16
view all 10 authors...
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#1Kelly E. Mercer (University of Arkansas for Medical Sciences)H-Index: 18
#2Sudeepa Bhattacharyya (University of Arkansas for Medical Sciences)H-Index: 16
Last. Martin J. J. Ronis (LSU Health Sciences Center New Orleans)H-Index: 48
view all 7 authors...
BACKGROUND: Soy infant formula contains isoflavones, which are able to bind to and activate estrogen receptor (ER) pathways. The mammary gland is sensitive to estrogens, raising concern that the use of soy formulas may promote premature development. OBJECTIVE: We aimed to determine if soy formula feeding increases mammary gland proliferation and differentiation in comparison to other infant postnatal diets. METHODS: White-Dutch Landrace piglets aged 2 d received either sow milk (Sow), or were pr...
3 CitationsSource
#1Tekeda F Ferguson (LSU: Louisiana State University)H-Index: 7
#2Erika M Rosen (LSU: Louisiana State University)H-Index: 1
Last. Patricia E. Molina (LSU: Louisiana State University)H-Index: 33
view all 9 authors...
AIM: This cross-sectional analysis of the New Orleans Alcohol Use in HIV (NOAH) study assesses whether current and lifetime alcohol use in people living with HIV (PLWH) are associated with greater liver disease and how hepatitis C-viral (HCV) co-infection (HIV/HCV+) modifies the association. METHODS: Alcohol use was measured by Lifetime Drinking History (LDH), a 30-day Timeline Followback calendar, the Alcohol Use Disorder Identification Test, and phosphatidylethanol. Liver disease was estimated...
2 CitationsSource
#1Martin J. J. Ronis (LSU Health Sciences Center New Orleans)H-Index: 48
#2James Watt (LSU Health Sciences Center New Orleans)H-Index: 4
Last. Larry W. Robertson (UI: University of Iowa)H-Index: 48
view all 8 authors...
Skeletal toxicity has been reported following exposure to polychlorinated biphenyl (PCB) mixtures. However, molecular mechanisms remain poorly understood. We exposed groups of male 4–5-week-old Sprague–Dawley rats to 3,3′, 4, 4′, 5-pentachlorobiphenyl (PCB 126), a dioxin-like coplanar PCB congener by a single i.p. injection of 5 µmol/kg in soy oil vehicle or vehicle alone. After 4 weeks, rats were euthanized. PCB exposure resulted in hypocalcemia (P < 0.05) and significant increases in serum PTH...
6 CitationsSource
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