Drew K. Seisler
Mayo Clinic
CancerInternal medicineSurgeryOncologyRandomized controlled trialPhysical therapyAdverse effectPlaceboChemotherapyCommon Terminology Criteria for Adverse EventsFOLFOXChemotherapy-induced peripheral neuropathyNeurotoxicityPeripheral neuropathyNauseaAntiemeticOxaliplatinLymphedemaIn patientAnesthesiaIncidence (epidemiology)Breast cancerClinical trialMedicineGastroenterology
Publications 49
#1Marie Vincenti (Mayo Clinic)H-Index: 1
#2Patrick W. O'Leary (Mayo Clinic)H-Index: 41
Last. Joan Wobig (Mayo Clinic)H-Index: 2
view all 7 authors...
Preservation of right ventricle function (RV) is a key to favorable outcome in Hypoplastic Left Heart Syndrome (HLHS), but methods to preserve or improve RV function are limited. Our goal was to assess the clinical and functional impact of autologous umbilical cord blood-derived mononuclear cells (UCB-MNC) therapy when given to patients with HLHS at Stage II surgery. UCB-MNC patients were enrolled prospectively in a phase I, FDA monitored trial as previously described (Burkhart et al., 2019). Ma...
#1Patrick W. O'Leary (Mayo Clinic)H-Index: 41
#2M. Yasir Qureshi (Mayo Clinic)H-Index: 5
Last. Angela R. MillerH-Index: 2
view all 15 authors...
Abstract null null Objective null To define the impact of tricuspid valve cone reconstruction (CR) on ventricular performance in Ebstein anomaly, both independently and after stem cell therapy. null null null Patients and Methods null The control group included 257 patients who had CR between June 2007 and December 2019. Ten subjects of a phase I stem cell therapy trial (May 2017 – March 2019) were compared with the controls to assess the echocardiographic impact on ventricular remodeling. null ...
#2Joseph A. Dearani (UR: University of Rochester)H-Index: 95
#5Bryan C. Cannon (UR: University of Rochester)H-Index: 30
Last. Karen Cavanaugh (Mayo Clinic)H-Index: 2
view all 13 authors...
Abstract Background The objective of this study is to assess the safety and early impact of intramyocardial delivery of autologous bone marrow-derived mononuclear cells (BM-MNC) at time of surgical Ebstein repair. Methods Patients with EA (ages 6 months to 30 years) scheduled to undergo repair of the TV were eligible to participate in this open label, non-randomized Phase I clinical trial. BM-MNC target dose was 1-3 million cells/kg. Ten patients have undergone surgical intervention and cell del...
#1Electra D. Paskett (OSU: Ohio State University)H-Index: 64
#2Jennifer Le-Rademacher (Mayo Clinic)H-Index: 16
Last. Charles L. Loprinzi (Mayo Clinic)H-Index: 113
view all 16 authors...
BACKGROUND Lymphedema affects many women who are treated for breast cancer. We examined the effectiveness of an education-only (EO) versus education plus sleeve compression/exercise intervention (lymphedema education and prevention [LEAP]) on lymphedema incidence and range of motion (ROM) in a group-randomized trial across 38 cooperative group sites. METHODS The treating institution was randomly assigned to either EO or LEAP by a study statistician. All patients at a treating institution partici...
#1Michelle J. Naughton (OSU: Ohio State University)H-Index: 16
#2Heshan Liu (Mayo Clinic)H-Index: 21
Last. Electra D. Paskett (OSU: Ohio State University)H-Index: 64
view all 16 authors...
Background Lymphedema is an adverse effect of breast cancer treatment that causes swelling and pain in the arm and hand. We tested 2 lymphedema prevention interventions and their impact on health-related quality of life (HRQOL) in a group-randomized trial at 38 cooperative group sites within the United States. Methods Patients were recruited before breast surgery. Sites were randomly assigned to education-only (EO) lymphedema prevention or education plus exercise and physical therapy (LEAP). Lym...
#1Marie Vincenti (UR: University of Rochester)
#2M. Yasir Qureshi (UR: University of Rochester)H-Index: 5
Last. Frank Cetta (UR: University of Rochester)H-Index: 46
view all 6 authors...
Decline of single ventricle systolic function after bidirectional cavopulmonary connection (BDCPC) is thought to be a transient phenomenon. We analyzed ventricular function after BDCPC according to ventricular morphology and correlated this evolution to long-term prognosis. A review from Mayo Clinic databases was performed. Visually estimated ejection fraction (EF) was reported from pre-BDCPC to pre-Fontan procedure. The last cardiovascular update was collected to assess long-term prognosis. A f...
#1J. Kellogg Parsons (Veterans Health Administration)H-Index: 14
#2David Zahrieh (Mayo Clinic)H-Index: 3
Last. James R. MarshallH-Index: 107
view all 20 authors...
Importance Guidelines endorsing vegetable-enriched diets to improve outcomes for prostate cancer survivors are based on expert opinion, preclinical studies, and observational data. Objective To determine the effect of a behavioral intervention that increased vegetable intake on cancer progression in men with early-stage prostate cancer. Design, Setting, and Participants The Men’s Eating and Living (MEAL) Study (CALGB 70807 [Alliance]) was a randomized clinical trial conducted at 91 US urology an...
#1Heidi D. Klepin (Wake Forest University)H-Index: 33
#2Ellen K. Ritchie (Cornell University)H-Index: 30
Last. Geoffrey L. UyH-Index: 37
view all 18 authors...
Abstract Objective To demonstrate feasibility of performing geriatric assessment (GA) in the National Clinical Trials Network (NCTN) and to explore the utility of GA to characterize treatment tolerance. Materials and methods We conducted a multisite companion study (CALGB 361006) to CALGB 11001, a phase 2 trial of adults ≥60 years old with newly diagnosed FLT3- mutated AML, testing the efficacy of adding sorafenib to intensive chemotherapy. On 361006, a GA was administered prior to induction and...
#1Robert E. SchoenH-Index: 71
#2Lisa A. BoardmanH-Index: 49
Last. Olivera J. FinnH-Index: 66
view all 16 authors...
#1Marie E. Wood (UVM: University of Vermont)H-Index: 22
#2Drew K. Seisler (Mayo Clinic)H-Index: 17
Last. James Roger Marshall (Roswell Park Cancer Institute)H-Index: 2
view all 15 authors...
1549Background: Vitamin D is safe and has breast cancer prevention properties. CALGB 70806 was a randomized phase II trial evaluating the effect of vit D on several breast cancer biomarkers (includ...
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