Internal medicine

Pathology

Archaeology

Diabetic foot

Diabetes mellitus

History

Endocrinology

Evidence-based practice

Surgery

Intensive care medicine

Evidence-based medicine

Alternative medicine

Compendium

Negative-pressure wound therapy

Clinical trial

Medicine

ADA Clinical Compendia

This treatise includes reviews of both of these new therapies by members of our author group (F.L.G. and M.E.E.) who participated in the clinical trials of the respective agents. Additionally, the use of negative pressure wound therapy (NPWT), which is also supported by evidence from RCTs, is reviewed. The final two sections of this compendium explore putative new, evidence-based therapies for DFUs that are in the pipeline and, most importantly, how we might engage digital technology and other aids to facilitate the prevention of DFU recurrence.

New Evidence-Based Therapies for Complex Diabetic Foot Wounds