Internal medicine

Sedation

Bradycardia

Dexmedetomidine

Blood pressure

Surgery

Intensive care medicine

Propofol

Mechanical ventilation

Intensive care unit

Cardiac surgery

Heart rate

Delirium

Anesthesia

Confidence interval

Medicine

British Journal of Anaesthesia

Guidelines have recommended the use of dexmedetomidine or propofol for sedation after cardiac surgery, and propofol monotherapy for other patients. Further outcome data are required for these drugs.

Outcomes of dexmedetomidine versus propofol sedation in critically ill adults requiring mechanical ventilation: a systematic review and meta-analysis of randomised controlled trials