gastrointestinal bleeding

blood loss

tranexamic

anti-xa

txa_112440

allogeneic blood

tranexamic acid txa

opcab

hb dl

thromboembolic

New England Journal of Medicine

Among patients undergoing noncardiac surgery, the incidence of the composite bleeding outcome was significantly lower with tranexamic acid than with placebo. Although the between-group difference in the composite cardiovascular outcome was small, the noninferiority of tranexamic acid was not established. (Funded by the Canadian Institutes of Health Research and others; POISE-3 ClinicalTrials.gov number, NCT03505723.).

Tranexamic Acid in Patients Undergoing Noncardiac Surgery