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ADVERTISEMENT RETURN TO ISSUEPREVThe HubNEXTThe Path to PaxlovidHow Pfizer scientists transformed an old drug lead into an oral COVID-19 antiviral.Bethany HalfordBethany HalfordMore by Bethany HalfordCite this: ACS Cent. Sci. 2022, 8, 4, 405–407Publication Date (Web):April 4, 2022Publication History Published online4 April 2022Published inissue 27 April 2022https://pubs.acs.org/doi/10.1021/acscentsci.2c00369https://doi.org/10.1021/acscentsci.2c00369newsACS PublicationsCopyright © 2022 American Chemical Society. This publication is licensed under CC-BY-NC-ND 4.0. License Summary*You are free to share (copy and redistribute) this article in any medium or format within the parameters below:Creative Commons (CC): This is a Creative Commons license.Attribution (BY): Credit must be given to the creator.Non-Commercial (NC): Only non-commercial uses of the work are permitted. No Derivatives (ND): Derivative works may be created for non-commercial purposes, but sharing is prohibited. View full license*DisclaimerThis summary highlights only some of the key features and terms of the actual license. It is not a license and has no legal value. Carefully review the actual license before using these materials. This publication is Open Access under the license indicated. Learn MoreArticle Views10339Altmetric-Citations25LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail PDF (1 MB) Get e-AlertscloseSUBJECTS:Antimicrobial agents,COVID-19,Ketones,Molecules,Peptides and proteins Get e-Alerts

The Path to Paxlovid