Internal medicine

Immunotherapy

Disease

Prostate cancer

Bioinformatics

Biology

Cancer

Oncology

Prostate

Management of prostate cancer

Medicine

The Lancet

The management of prostate cancer continues to evolve rapidly, with substantial advances being made in understanding the genomic landscape and biology underpinning both primary and metastatic prostate cancer. Similarly, the emergence of more sensitive imaging methods has improved diagnostic and staging accuracy and refined surveillance strategies. These advances have introduced personalised therapeutics to clinical practice, with treatments targeting genomic alterations in DNA repair pathways now clinically validated.