A β-hairpin peptide with pH-controlled affinity for tumor cells
Abstract
Considering that the pH in the tumor microenvironment is dysregulated, we designed a β-hairpin peptide (SSRFEWEFESSDPRGDPSSRFEWEFESS). The configuration of the peptide switched from a flexible linear to a rigid loop structure under weakly acidic conditions. The peptide internalized by tumor cells increased significantly under weakly acidic...
Paper Details
Title
A β-hairpin peptide with pH-controlled affinity for tumor cells
Published Date
Jan 1, 2022
Journal
Volume
58
Issue
4
Pages
505 - 508
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Notes
History