Original paper
Solid-liquid equilibrium of nicotinamide in water-ethanol and water-propylene glycol mixtures
Abstract
Nicotinamide is an active pharmaceutical ingredient (API) with high structural complexity and one form of vitamin B3 still poorly understood. For the pharmaceutical industry, the solubility knowledge of APIs is truly relevant for their production, bioavailability, and to be careful with polymorphs formation. In this context, it was determined nicotinamide solid–liquid equilibrium in temperatures from 20 to 50 °C for two solvent systems:...
Paper Details
Title
Solid-liquid equilibrium of nicotinamide in water-ethanol and water-propylene glycol mixtures
Published Date
Jan 1, 2022
Journal
Volume
345
Pages
117799 - 117799
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Notes
History