Low Serum C3 Pauci-Immune Glomerulonephritis: High Histopathological Activity and Lower Rates of Response to Standard Therapies

We thank you for the opportunity to respond to the letter by Pr Jean-François Augusto. Low serum complement pauci-immune glomerulonephritis (PIGN) is increasingly being recognized as an entity with distinct characteristics, in terms of its clinical picture and response to currently used immunosuppressive regimens.S1,1Brilland B. Wacrenier S. Henry N. et al.Low complement C3 levels at diagnosis of ANCA-associated glomerulonephritis, a specific...