Adiposity and cancer: a Mendelian randomization analysis in the UK biobank

Volume: 45, Issue: 12, Pages: 2657 - 2665
Published: Aug 27, 2021
Abstract
Observational and Mendelian randomization (MR) studies link obesity and cancer, but it remains unclear whether these depend upon related metabolic abnormalities.We used information from 321,472 participants in the UK biobank, including 30,561 cases of obesity-related cancer. We constructed three genetic instruments reflecting higher adiposity together with either "unfavourable" (82 SNPs), "favourable" (24 SNPs) or "neutral" metabolic profile (25...
Paper Details
Title
Adiposity and cancer: a Mendelian randomization analysis in the UK biobank
Published Date
Aug 27, 2021
Volume
45
Issue
12
Pages
2657 - 2665
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