Genomics

Structural genomics

Effector

Biology

Gene

Comparative genomics

Genome

Protein structure prediction

Pathogen

Structural biology

Protein structure

Computational biology

Cell biology

Fungal pathogen

Genetics

Biochemistry

Molecular Plant-Microbe Interactions

Structural biology has the potential to illuminate the evolution of pathogen effectors and their commonalities that cannot be readily detected at the primary sequence level. Recent breakthroughs in protein structure modeling have demonstrated the feasibility to predict the protein folds without depending on homologous templates. These advances enabled a genome-wide computational structural biology approach to help understand proteins based on their predicted folds. In this study, we employed structure prediction methods on the secretome of the destructive fungal pathogen

Computational Structural Genomics Unravels Common Folds and Novel Families in the Secretome of Fungal Phytopathogen<i>Magnaporthe oryzae</i>

Computational Structural Genomics Unravels Common Folds and Novel Families in the Secretome of Fungal PhytopathogenMagnaporthe oryzae