Internal medicine

Pregnane X receptor

Receptor

Peroxisome proliferator-activated receptor

Constitutive androstane receptor

In vivo

Mechanism of action

Liver injury

Rodent

Nuclear receptor

Transcription factor

Biology

Gene

Mode of action

Endocrinology

Apoptosis

Mdm2

Ecology

In vitro

Hepatocyte

Androstane

Phenobarbital

Cancer research

Genetics

Biochemistry

Medicine

Pharmacology

Critical Reviews in Toxicology

(2021). Critical evaluation of the human relevance of the mode of action for rodent liver tumor formation by activators of the constitutive androstane receptor (CAR) Critical Reviews in Toxicology: Vol. 51, No. 5, pp. 373-394.

Critical evaluation of the human relevance of the mode of action for rodent liver tumor formation by activators of the constitutive androstane receptor (CAR)