Physics

Nanotechnology

Organic chemistry

Combinatorial chemistry

Photoredox catalysis

Photocatalysis

Visible spectrum

Engineering

Catalysis

Biochemical engineering

Chemistry

Materials science

Natural product

Art history

Optoelectronics

The Renaissance

Organic synthesis

Photochemistry

Chemical Reviews

Recent progress in the development of photocatalytic reactions promoted by visible light is leading to a renaissance in the use of photochemistry in the construction of structurally elaborate organic molecules. Because of the rich functionality found in natural products, studies in natural product total synthesis provide useful insights into functional group compatibility of these new photocatalytic methods as well as their impact on synthetic strategy. In this review, we examine total syntheses published through the end of 2020 that employ a visible-light photoredox catalytic step. To assist someone interested in employing the photocatalytic steps discussed, the review is organized largely by the nature of the bond formed in the photocatalytic step.

Strategic Use of Visible-Light Photoredox Catalysis in Natural Product Synthesis