Gene

Hypertrophic cardiomyopathy

Shock (circulatory)

Tachycardia

Cardiology

Biochemistry

Anesthesia

White (mutation)

Cardiogenic shock

Heart failure

Supraventricular tachycardia

Myocardial infarction

Internal medicine

Electrocardiography

Cardiomyopathy

Medicine

Chemistry

Ventricular fibrillation

Neonatal Medicine

We present the case of a healthy 28-day-old female full-term neonate who was admitted to the neonatal intensive care unit for severe metabolic acidosis, hypoglycemia, and an initial sinus rhythm. The first diagnostic hypothesis was hypovolemic shock, and fluid resuscitation was started immediately. During fluid therapy, cardiovascular collapse occurred with supraventricular tachycardia. The latter was successfully treated with adenosine and beta-blockers. After 8 days, electrocardiography showed ventricular pre-excitation, and Wolff-Parkinson-White syndrome was diagnosed. A novel variant of the MYL2 gene that is related to hypertrophic cardiomyopathy and conduction defect was found after discharge. Cardiogenic shock should be considered, despite being a rare cause of shock in neonates. Keywords: Shock, cardiogenic; Cardiomyopathy, hypertrophic; Acidosis; Tachycardia, supraventricular; Wolff-Parkinson-White syndrome

A Neonate Diagnosed with Wolff-Parkinson-White Syndrome Presenting with Cardiogenic Shock