Portal hypertension in cirrhosis: Pathophysiological mechanisms and therapy
Abstract
Portal hypertension, defined as increased pressure in the portal vein, develops as a consequence of increased intrahepatic vascular resistance due to the dysregulation of liver sinusoidal endothelial cells (LSECs) and hepatic stellate cells (HSCs), frequently arising from chronic liver diseases. Extrahepatic haemodynamic changes contribute to the aggravation of portal hypertension. The pathogenic complexity of portal hypertension and the...
Paper Details
Title
Portal hypertension in cirrhosis: Pathophysiological mechanisms and therapy
Published Date
Aug 1, 2021
Journal
Volume
3
Issue
4
Pages
100316 - 100316
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History