Phylogenetic tree

Bacterial genome size

Pipeline (software)

Evolutionary biology

Biology

Phylogenetics

Phylum

Gene

Genome

Core (optical fiber)

Programming language

Computer science

Clade

Phylogenomics

Computational biology

Genetics

Telecommunications

The Journal of Microbiology

Phylogenomic tree reconstruction has recently become a routine and critical task to elucidate the evolutionary relationships among bacterial species. The most widely used method utilizes the concatenated core genes, universally present in a single-copy throughout the bacterial domain. In our previous study, a bioinformatics pipeline termed Up-to-date Bacterial Core Genes (UBCG) was developed with a set of bacterial core genes selected from 1,429 species covering 28 phyla. In this study, we revised a new bacterial core gene set, named UBCG2, that was selected from the more extensive genome sequence set belonging to 3,508 species spanning 43 phyla. UBCG2 comprises 81 genes with nine Clusters of Orthologous Groups of proteins (COGs) functional categories. The new gene set and complete pipeline are available at http://leb.snu.ac.kr/ubcg2 .

UBCG2: Up-to-date bacterial core genes and pipeline for phylogenomic analysis