Handedness and depression: A meta-analysis across 87 studies.

Published on Nov 1, 2021
· DOI :10.1016/J.JAD.2021.07.052
Julian Packheiser8
Estimated H-index: 8
,
Judith Schmitz10
Estimated H-index: 10
+ 5 AuthorsSebastian Ocklenburg31
Estimated H-index: 31
Source
Abstract
References140
Newest
#1Sebastian Ocklenburg (RUB: Ruhr University Bochum)H-Index: 31
#2Gesa Berretz (RUB: Ruhr University Bochum)H-Index: 4
Last. Patrick Friedrich (University of Bordeaux)H-Index: 11
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In the 2010s, significant progress has been made in several key areas of laterality research, including neuroimaging, genetics and comparative research. In the present article, we discuss which tre...
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#1Judith Schmitz (St And: University of St Andrews)H-Index: 10
#2Mo Zheng (CUHK: The Chinese University of Hong Kong)H-Index: 8
Last. Silvia Paracchini (St And: University of St Andrews)H-Index: 30
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The heritability of handedness, the most commonly investigated lateralised phenotype, has been consistently estimated to be ~25%. Handedness is linked to brain asymmetries such as hemispheric dominance for language and it has been associated to psychiatric and neurodevelopmental disorders. Here, we investigated the genetics of handedness as well as foot and eye preference and their relationship with neurodevelopmental phenotypes. Parental left-side preference increased the chance of an individua...
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#1Marietta Papadatou-Pastou (UoA: National and Kapodistrian University of Athens)H-Index: 15
#2Despoina-Athanasia Panagiotidou (UoA: National and Kapodistrian University of Athens)H-Index: 1
Last. Giannis Karagiannakis (UoA: National and Kapodistrian University of Athens)H-Index: 3
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Increased rates of atypical handedness are observed in neurotypical individuals who are low-performing in mathematical tasks as well as in individuals with special educational needs, such as dyslexia. This is the first investigation of handedness in individuals with Mathematical Learning Difficulties (MLD). We report three new studies (N = 134; N = 1,893; N = 153) and two sets of meta-analyses (22 studies; N = 3,667). No difference in atypical hand preference between MLD and Typically Achieving ...
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Last. Alan A. Beaton (Aberystwyth University)H-Index: 15
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The Geschwind-Behan-Galaburda and sexual differentiation models predict an association between elevated foetal androgen exposure and left-handedness whereas the callosal hypothesis predicts the opp...
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#1Julian Packheiser (RUB: Ruhr University Bochum)H-Index: 8
#2Judith Schmitz (St And: University of St Andrews)H-Index: 10
Last. Sebastian Ocklenburg (University of Duisburg-Essen)H-Index: 31
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Human lateral preferences, such as handedness and footedness, have interested researchers for decades due to their pronounced asymmetries at the population level. While there are good estimates on the prevalence of handedness in the population, there is no large-scale estimation on the prevalence of footedness. Furthermore, the relationship between footedness and handedness still remains elusive. Here, we conducted meta-analyses with four different classification systems for footedness on 145,13...
7 CitationsSource
#1Julian Packheiser (RUB: Ruhr University Bochum)H-Index: 8
#2Judith Schmitz (St And: University of St Andrews)H-Index: 10
Last. Sebastian Ocklenburg (University of Duisburg-Essen)H-Index: 31
view all 6 authors...
Human language is dominantly processed in the left cerebral hemisphere in most of the population. While several studies have suggested that there are higher rates of atypical right-hemispheric language lateralization in left-/mixed-handers, an accurate estimate of this association from a large sample is still missing. In this study, we comprised data from 1,554 individuals sampled in three previous studies in which language lateralization measured via dichotic listening, handedness and footednes...
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#1Mei-Li Hsieh (NCTU: National Chiao Tung University)H-Index: 8
#2Alex Kaiser (RPI: Rensselaer Polytechnic Institute)H-Index: 1
Last. Shawn-Yu Lin (NCTU: National Chiao Tung University)H-Index: 36
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The tantalizing possibility of 31% solar-to-electric power conversion efficiency in thin film crystalline silicon solar cell architectures relies essentially on solar absorption well beyond the Lambertian light trapping limit (Bhattacharya and John in Nat Sci Rep 9:12482, 2019). Up to now, no solar cell architecture has exhibited above-Lambertian solar absorption, integrated over the broad solar spectrum. In this work, we experimentally demonstrate two types of photonic crystal (PhC) solar cells...
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#1Onur Güntürkün (RUB: Ruhr University Bochum)H-Index: 77
#2Felix Ströckens (RUB: Ruhr University Bochum)H-Index: 10
Last. Sebastian Ocklenburg (RUB: Ruhr University Bochum)H-Index: 31
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Comparative studies on brain asymmetry date back to the 19th century but then largely disappeared due to the assumption that lateralization is uniquely human. Since the reemergence of this field in the 1970s, we learned that left-right differences of brain and behavior exist throughout the animal kingdom and pay off in terms of sensory, cognitive, and motor efficiency. Ontogenetically, lateralization starts in many species with asymmetrical expression patterns of genes within the Nodal cascade t...
54 CitationsSource
#1Marietta Papadatou-Pastou (UoA: National and Kapodistrian University of Athens)H-Index: 15
#2Eleni Ntolka (UoA: National and Kapodistrian University of Athens)H-Index: 2
Last. Silvia Paracchini (St And: University of St Andrews)H-Index: 30
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Across time and place, right hand preference has been the norm, but what is the precise prevalence of left- and right-handedness? Frequency of left-handedness has shaped and underpinned different fields of research, from cognitive neuroscience to human evolution, but reliable distributional estimates are still lacking. While hundreds of empirical studies have assessed handedness, a large-scale, comprehensive review of the prevalence of handedness and the factors that moderate it, is currently mi...
54 CitationsSource
#1Julian Packheiser (RUB: Ruhr University Bochum)H-Index: 8
#2Judith Schmitz (St And: University of St Andrews)H-Index: 10
Last. Sebastian Ocklenburg (University of Duisburg-Essen)H-Index: 31
view all 7 authors...
The Edinburgh Handedness Inventory (EHI) and the Waterloo Footedness Questionnaire (WFQ) are two of the most widely used questionnaire to assess lateralized everyday behavior in human participants. However, it is unclear to what extent the specific behavior assessed in these questionnaires elicit lateralized neural activity when performed in real-life situations. To illuminate this unresolved issue, we assessed EEG alpha and beta asymmetries during real-life performance of the behaviors assessed...
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#1Kexin Huang (Xidian University)H-Index: 3
#2Yafei Kang (Xidian University)H-Index: 3
Last. Liyu Huang (Xidian University)H-Index: 12
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Abstract Schizophrenia (SZ), bipolar disorder (BD) and major depression disorder (MDD) have been regarded as highly diverged independent entities in current psychiatric diagnosis. However, ample new evidence suggests that they may have common biological traits. Neuroimaging studies showed that psychiatric disorders might associated with altered grey matter (GM) asymmetry compared to controls; however, the degree to which SZ, BD and MDD have common and/or distinct asymmetrical alterations in GM i...
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