Internal medicine

Vesicle

Microvesicles

Macrophage

Fibrosis

Membrane

Myocardial infarction

Biology

Gene

Cardiology

microRNA

Chemistry

In vitro

Extracellular

Myocardial fibrosis

Extracellular vesicle

Cell biology

Extracellular vesicles

Biochemistry

Medicine

Theranostics

This study aimed to explore the role of circular RNAs (circRNAs) in M2 macrophage (M2M)-derived small extracellular vesicles (SEVs) in myocardial fibrosis development.

CircUbe3a from M2 macrophage-derived small extracellular vesicles mediates myocardial fibrosis after acute myocardial infarction