Multi-step cefazolin sodium release from bioactive TiO2 nanotubes: Surface and polymer coverage effects

Bacterial implant-related infections have been pointed out as the leading cause of metal implant failure. Recently, nanotexturization of biomaterials surface associated with antibiotic loading revealed itself as a promising strategy for enhancing osseointegration while mitigating bacterial infections. However, fewer studies describe the effects of multi-step local drug delivery. This study investigates 1 mg Cefazolin Sodium (CS) release from...