Chronic Nrf2 deficiency affects age- and gender- dependent bone and cartilage acquisition in murine femur

Introduction Nuclear factor erythroid 2–related factor 2 (Nrf2) is crucial for maintaining cellular redox homeostasis and it also affects bone and cartilage metabolism. However, its age- and gender- dependent influence has yet to be described. The aim of this study was to investigate the role of Nrf2 on bone and cartilage acquisition in young and elderly mice by using a micro-computed tomography...