AAA ATPases as therapeutic targets: Structure, functions, and small-molecule inhibitors

Volume: 219, Pages: 113446 - 113446
Published: Jul 1, 2021
Abstract
ATPases Associated with Diverse Cellular Activity (AAA ATPase) are essential enzymes found in all organisms. They are involved in various processes such as DNA replication, protein degradation, membrane fusion, microtubule serving, peroxisome biogenesis, signal transduction, and the regulation of gene expression. Due to the importance of AAA ATPases, several researchers identified and developed small-molecule inhibitors against these enzymes. We...
Paper Details
Title
AAA ATPases as therapeutic targets: Structure, functions, and small-molecule inhibitors
Published Date
Jul 1, 2021
Volume
219
Pages
113446 - 113446
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