High turnover of types III and VI collagen in progressive idiopathic pulmonary fibrosis

Background and objective Prediction of idiopathic pulmonary fibrosis (IPF) progression is vital for the choice and timing of treatment and patient follow‐up. This could potentially be achieved by prognostic blood biomarkers of extracellular matrix (ECM) remodelling. Methods Neoepitope biomarkers of types III and VI collagen turnover (C3M, C6M, PRO‐C3 and PRO‐C6) were measured in 185 patients with newly diagnosed IPF. Disease severity at baseline...