Review paper

Sodium channelopathies of skeletal muscle and brain

Volume: 101, Issue: 4, Pages: 1633 - 1689
Published: Oct 1, 2021
Abstract
Voltage-gated sodium channels initiate action potentials in nerve, skeletal muscle, and other electrically excitable cells. Mutations in them cause a wide range of diseases. These channelopathy mutations affect every aspect of sodium channel function, including voltage sensing, voltage-dependent activation, ion conductance, fast and slow inactivation, and both biosynthesis and assembly. Mutations that cause different forms of periodic paralysis...
Paper Details
Title
Sodium channelopathies of skeletal muscle and brain
Published Date
Oct 1, 2021
Volume
101
Issue
4
Pages
1633 - 1689
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