Wireless

Biology

Operating system

World Wide Web

Political science

Throughput

Information retrieval

Data science

Computer science

DNA sequencing

Genetics

Reading (process)

GigaScience

Since the original publication of the VCF and SAM formats, an explosion of software tools have been created to process these data files. To facilitate this a library was produced out of the original SAMtools implementation, with a focus on performance and robustness. The file formats themselves have become international standards under the jurisdiction of the Global Alliance for Genomics and Health.

HTSlib: C library for reading/writing high-throughput sequencing data