Catalysis

Intramolecular force

Palladium

Heck reaction

Total synthesis

Stereochemistry

Combinatorial chemistry

Organic chemistry

Chemistry

European Journal of Organic Chemistry

This review highlights the application of intramolecular Heck reaction in total synthesis of natural products which were successfully synthesized in recent years (2013 to 2019). Heck cyclization was used as one of the strategic steps for constructions of wide variety of cyclic scaffolds essential for preparation of different natural products.

Intramolecular Heck Reaction in Total Synthesis of Natural Products: An Update