Internal medicine

Sociology

Biology

Gene

Genotype

Ethnic group

Anthropology

Ivacaftor

Cystic fibrosis

Cystic fibrosis transmembrane conductance regulator

Botany

Genetics

Medicine

Race (biology)

Pediatric Pulmonology

Cystic fibrosis transmembrane conductance regulator (CFTR) modulators are disease-modifying medications for cystic fibrosis (CF) and are shown to be efficacious for only specific CFTR mutations. CFTR mutation frequency varies by ancestry, which is different from but related to demographic racial and ethnic group. Eligibility for CFTR modulator therapy has not been previously reported by race and ethnicity.

Cystic fibrosis patients of minority race and ethnicity less likely eligible for CFTR modulators based on <i>CFTR</i> genotype

Cystic fibrosis patients of minority race and ethnicity less likely eligible for CFTR modulators based on CFTR genotype