Suppression of autophagy through JAK2/STAT3 contributes to the therapeutic action of rhynchophylline on asthma

Volume: 21, Issue: 1
Published: Jan 7, 2021
Abstract
Background Asthma is a chronic inflammatory disease characterized by airway remodeling and inflammation. Rhynchophylline is a kind of indole alkaloid isolated from Uncaria rhynchophylla . Here we investigated the effect of rhynchophylline on autophagy in asthma. Methods A mice model of asthma was established by ovalbumin challenge. Histopathological changes were assessed by hematoxylin-eosin staining, periodic acid-schiff staining and Masson...
Paper Details
Title
Suppression of autophagy through JAK2/STAT3 contributes to the therapeutic action of rhynchophylline on asthma
Published Date
Jan 7, 2021
Volume
21
Issue
1
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