Nuclear chemistry

Raman spectroscopy

Dielectric spectroscopy

Engineering

Oxide

Electrochemistry

Metallurgy

Materials science

Chromatography

Graphene

Cyclic voltammetry

Nanocomposite

Chemical engineering

Electrochemical gas sensor

Physical chemistry

Physics

Nanotechnology

Optics

Composite material

Analytical Chemistry (journal)

Chemistry

Scanning electron microscope

Linear sweep voltammetry

Electrode

Fourier transform infrared spectroscopy

Differential pulse voltammetry

Detection limit

Microchimica Acta

Polymelamine formaldehyde/graphene oxide (PMF/GO) nanocomposite was used, for the first time, to study the ultrasensitive and selective electrochemical detection of oxycodone (OXC). The successful characterization of PMF/GO was verified based on scanning electron microscopy (SEM), transmission electron microscopy (TEM), Fourier transform infrared (FT-IR), X-ray diffraction (XRD), energy-dispersive spectroscopy (EDS), and Raman spectroscopy. The modified GCE (PMF/GO-GCE) proved its electrocatalytic effect on OXC determination according to cyclic, linear sweep, and differential pulse voltammetry (CV, LSV, and DPV) and electrochemical impedance spectroscopy (EIS) studies. The developed sensor under optimal conditions offered a linear relationship in a limited range of 0.01 to 45 μmol L−1 with the limit of detection (LOD) of 2.0 nmol L−1. The proposed PMF/GO-GCE sensor was effectively employed for the OXC detection in human urine and serum samples.

Electrochemical sensor based on glassy carbon electrode modified by polymelamine formaldehyde/graphene oxide nanocomposite for ultrasensitive detection of oxycodone