Fabrication of tri-layered electrospun polycaprolactone mats with improved sustained drug release profile
Abstract
Modulation of initial burst and long term release from electrospun fibrous mats can be achieved by sandwiching the drug loaded mats between hydrophobic layers of fibrous polycaprolactone (PCL). Ibuprofen (IBU) loaded PCL fibrous mats (12% PCL-IBU) were sandwiched between fibrous polycaprolactone layers during the process of electrospinning, by varying the polymer concentrations (10% (w/v), 12% (w/v)) and volume of coat (1 ml, 2 ml) in flanking...
Paper Details
Title
Fabrication of tri-layered electrospun polycaprolactone mats with improved sustained drug release profile
Published Date
Oct 23, 2020
Journal
Volume
10
Issue
1
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