Organic chemistry

Combinatorial chemistry

Mannich reaction

Enantioselective synthesis

Catalysis

Chemistry

Squaramide

Bifunctional

Organocatalysis

Advanced Synthesis & Catalysis

Bifunctional squaramides as a branch of organo‐catalysts showed powerful strategies in the art of asymmetric synthesis, and they have been proved to be highly efficient and versatile catalysts for constructing complex molecular structures and chiral biologically active compounds. In this review, we summarized recent advances in bifunctional squaramide‐catalyzed asymmetric Mannich reactions. magnified image

Recent Advances in Squaramide‐Catalyzed Asymmetric Mannich Reactions