Stimulation of Posterior Thalamic Nuclei Induces Photophobic Behavior in Mice

Objective A hallmark of migraine is photophobia. In mice, photophobia‐like behavior is induced by calcitonin gene‐related peptide (CGRP), a neuropeptide known to be a key player in migraine. In this study, we sought to identify sites within the brain from which CGRP could induce photophobia. Design We focused on the posterior thalamic region, which contains neurons responsive to both light and dural stimulation and has CGRP binding sites. We...