Gradient composite film with calcium phosphate silicate for improved tendon -to-Bone intergration

The tendon enthesis is a very complex tissue interface that connects a flexible tissue (tendon) to a stiff tissue (bone). Few available forms of gradient scaffolds with multiple components have been fabricated for applications in vivo because of the complexities of enthesis. In the present work, gradient-poly(ε-caprolactone)/calcium phosphate silicate (G-P/C) composite films were fabricated with tape casting technique. Films with different P/C...