Gene

Phenol

Engineering

Chloroform

Biology

Yield (engineering)

Metallurgy

Materials science

Chromatography

DNA extraction

Biochemistry

Computational biology

Biochemical engineering

Extraction (chemistry)

Organic chemistry

Reagent

Chemistry

Polymerase chain reaction

American Journal of Biomedical Science & Research

Since the first DNA extraction performed by Friedrich Miescher in 1869, scientists have made extraordinary progress in designing extraction methods that are more reliable, easier and faster to perform, more cost-effective and produce a higher yield. The classic liquid-liquid DNA extraction method involves the use of organic and inorganic reagents such as phenol-chloroform which pose a toxic threat to humans.

The Evolution of DNA Extraction Methods