Kidney

Type 2 diabetes

Hyperuricemia

Kidney disease

Gout

Endocrinology

Urology

Allopurinol

Internal medicine

Medicine

Renal function

Uric acid

Disease

Diabetes mellitus

New England Journal of Medicine

Higher serum urate levels are associated with an increased risk of diabetic kidney disease. Lowering of the serum urate level with allopurinol may slow the decrease in the glomerular filtration rate (GFR) in persons with type 1 diabetes and early-to-moderate diabetic kidney disease.

Serum Urate Lowering with Allopurinol and Kidney Function in Type 1 Diabetes