venous sinus

Canadian Journal of Ophthalmology

ObjectiveWhether transverse venous sinus stenosis (TVSS) causes idiopathic intracranial hypertension (IIH) or is an effect of the increased intracranial pressures is controversial. The purpose of this study was to assess the feasibility of serial imaging in patients with IIH on medical management.Design and ParticipantsPatients found to have IIH and TVSS on contrast-enhanced magnetic resonance venography (CEMRV) were recruited in a prospective cohort study. Patients were medically managed and followed with a CEMRV immediately after lumbar puncture, 3–6 months after diagnosis with resolution of IIH symptoms, and 1 year after diagnosis. Ophthalmological data were collected at the time of diagnosis, 3–6 months after diagnosis, and 1 year after diagnosis. Feasibility data, including patient recruitment rate, barriers, and logistical issues, were recorded.ResultsTwenty patients with suspected IIH were screened, and 5 of 7 (71.4%; 95% confidence interval: 36.21–100) eligible patients were enrolled in 1 year, at completion. All recruited patients had clinical resolution of their IIH on medical therapy, and none of them had any obvious change in their TVSS.ConclusionsProspective examination of TVSS with serial magnetic resonance imaging in patients with IIH is feasible. TVSS in patients with IIH did not show any change, despite clinical improvement on medical management in all participants.RésuméObjectifOn ne sait toujours pas avec certitude si c'est la sténose du sinus transverse (STT) qui entraîne l'hypertension intracrânienne idiopathique (HII) ou si la STT découle de l'augmentation de la pression intracrânienne. Notre étude visait donc à évaluer la faisabilité de réaliser une imagerie en série de patients présentant une HII qui faisaient l'objet d'une prise en charge médicale.Nature et participantsDes patients qui présentaient à la fois une HII et une STT à la phlébographie par résonance magnétique avec injection de produit de contraste (PRMPC) ont été recrutés dans le cadre d'une étude prospective de cohortes. Les p...

Transverse venous sinus stenosis in idiopathic intracranial hypertension: a prospective pilot study