Malignancy

Macrophage activation syndrome

Adult-onset Still's disease

Pediatrics

Arthritis

Internal medicine

Medicine

Disease

Annals of the Rheumatic Diseases

The best cut-off value of HScore was 169, with a sensitivity of 93% and a specificity of 86% when it was developed. 6The cutoff was set at 190.5 and yielded a sensitivity of 96.7% and a specificity of 98.4% when tested in a group of Turkish patients with MAS. 7 Our results indicate that HScore is suitable for detecting AOSD-MAS but with a lower cut-off value.Indeed, different patients' selection criteria, different disease status and different underlying diseases may result in quite different conclusions.Further studies are needed to validate these different scoring tools.

Comparison of MS score and HScore for the diagnosis of adult-onset Still’s disease-associated macrophage activation syndrome