Context (archaeology)

Adverse effect

Erythema

Biology

Surgery

Respirator

Skin reaction

Crossover study

Dermatology

Coronavirus disease 2019 (COVID-19)

Placebo

Paleontology

Alternative medicine

Organic chemistry

Stratum corneum

Infectious disease (medical specialty)

Internal medicine

Transepidermal water loss

Medicine

Chemistry

Disease

Pathology

Contact Dermatitis

In the context of the COVID-19 pandemic, cases of adverse skin reactions related to the wearing of masks have been observed.To analyze the short-term effects of N95 respirators and medical masks, respectively, on skin physiological properties and to report adverse skin reactions caused by the protective equipment.This study used a randomized crossover design with repeated measurements. Twenty healthy Chinese volunteers were recruited. Skin parameters were measured on areas covered by the respective masks and on uncovered skin 2 and 4 hours after donning, and 0.5 and 1 hour after removing the masks, including skin hydration, transepidermal water loss (TEWL), erythema, pH, and sebum secretion. Adverse reactions were clinically assessed, and perceived discomfort and non-compliance measured.Skin hydration, TEWL, and pH increased significantly with wearing the protective equipment. Erythema values increased from baseline. Sebum secretion increased both on the covered and uncovered skin with equipment-wearing. There was no significant difference in physiological values between the two types of equipment. More adverse reactions were reported following a N95 mask use than the use of a medical mask, with a higher score of discomfort and non-compliance.This study demonstrates that skin biophysical characters change as a result of wearing a mask or respirator. N95 respirators were associated with more skin reactions than medical masks.

Short‐term skin reactions following use of <scp>N95</scp> respirators and medical masks

Short‐term skin reactions following use of N95 respirators and medical masks