Fibromyalgia

Chronic fatigue syndrome

Economic growth

Psychiatry

Intensive care medicine

Physical therapy

Health care

Economics

Chronic pain

Musculoskeletal pain

Medicine

Annals of Internal Medicine

Fibromyalgia is characterized by chronic, widespread musculoskeletal pain and associated fatigue, sleep disturbances, and other cognitive and somatic symptoms. For many patients, these symptoms persist for years and lead to frequent health care use; for some, fibromyalgia and its symptoms can be debilitating. Although many treatments are available, management remains challenging. This article highlights the clinical features of fibromyalgia, discusses diagnostic criteria and their evolution, and reviews treatment options.