Palmitic acid damages gut epithelium integrity and initiates inflammatory cytokine production
Volume: 1865, Issue: 2, Pages: 158530 - 158530
Published: Feb 1, 2020
Abstract
The mechanisms leading to the low-grade inflammation observed during obesity are not fully understood. Seeking the initiating events, we tested the hypothesis that the intestine could be damaged by repeated lipid supply and therefore participate in inflammation. In mice, 1–5 palm oil gavages increased intestinal permeability via decreased expression and mislocalization of junctional proteins at the cell–cell contacts; altered the intestinal...
Paper Details
Title
Palmitic acid damages gut epithelium integrity and initiates inflammatory cytokine production
Published Date
Feb 1, 2020
Volume
1865
Issue
2
Pages
158530 - 158530
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