Menthol inhibits oxidative stress and inflammation in acetic acid-induced colitis in rat colonic mucosa.

Inflammatory bowel diseases (IBD) such as ulcerative colitis and Crohn's disease are characterized by chronic inflammation of the gastrointestinal system. There is no permanent cure from IBD except constant medication or surgery to keep the disease in remission. In the present study, the effect of menthol, a major ingredient of peppermint has been investigated in acetic acid-induced colitis model in Wistar rats. Menthol (50 mg/kg/day) was orally...